Abstract:Objective To investigate the effect of contact lens on the repair of corneal injury in patients with pterygium. Methods A total of 54 eyes of 52 patients with recurrent pterygium who were treated in the Outpatient Department of People′s Hospital of Beijing Daxing District from March 2016 to March 2018 were randomly divided into group A (28 eyes) and group B (26 eyes). The pterygium resection was performed in both groups, and the conjunctival flap with some limbal stem cells was taken and sutured on the sclera surface of the operation area. Group A was treated with contact lens for 5 days, and group B was routinely covered. The postoperative corneal irritation, corneal wound healing and dry eye syndrome were observed. Results On the first day after operation, the scores of corneal irritation symptoms in the two groups included eye pain, foreign body sensation, photophobia and tears, with significant difference (P < 0.05); on the third and fifth day after operation, there was no significant difference in the scores of corneal irritation symptoms between the two groups (P > 0.05). The scores of corneal irritation symptoms such as eye pain, foreign body sensation, photophobia and tear in both groups decreased with the prolongation of postoperative time. On the first day after operation, the corneal epithelial healing rate of the two groups had significant difference (P < 0.05), and the corneal epithelial healing rate of group A was significantly higher than that of group B (P < 0.05); the corneal epithelial healing rate of the two groups on the third and fifth day had no significant difference (P > 0.05); the corneal epithelial healing rate of the two groups on the first, third and fifth day after operation had significant difference (P < 0.05). There was no significant difference in subjective symptom score, corneal fluorescence staining (FL), tear break-up time (BUT) and Schirmer I test (SIt) between the two groups (P > 0.05). There were significant differences in subjective symptom score, FL and BUT between the two groups (P < 0.05), and group B were higher or longer than group A. Compared with pre-operation, there were significant differences in subjective symptom score, FL, BUT and SIt between the two groups (P < 0.05), and postoperative were higher or longer than preoperative. Conclusion Contact lens can significantly improve the corneal irritation sympotoms after operation in patients with pterygium, promote the repair of corneal injury and reduce postoperative discomfort.