A multicenter case-control study on the association between five categories of common fruits and bladder cancer
LING Qi1 WU Yongding2 QIN Guoqiang3
1.Administrative Office, Guangzhou Hospital of Integrated Chinese and Western Medicine, Guangdong Province, Guangzhou 510800, China;
2.Guangdong Key Laboratory of Clinical Molecular Medicine and Diagnostics, Guangzhou First People′s Hospital the Second Affiliated Hospital of South China University of Technology, Guangdong Province, Guangzhou 510180, China;
3.Department of Urology, Guangzhou Panyu Central Hospital, Guangdong Province, Guangzhou 511400, China
Abstract：Objective To study the relationship between five kinds of fruits and the incidence of bladder cancer. Methods A multicenter case-control study was conducted from September 2005 to June 2012. Four hundred and thirty-two cases of bladder cancer and 392 cases of non bladder cancer were recruited in Guangzhou First People′s Hospital, the Second Affiliated Hospital of Central South University, Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology and the First Affiliated Hospital of Zhejiang University. Patients with bladder cancer were classified as experimental group, and non bladder cancer patients were classified as control group. Patients of two groups were investigated and data was collected for statistical analysis. Results The response rate and the effective rate of questionnaire of the experimental group were 99.1% and 100.0%, and those of the control group were 99.5% and 100.0% respectively. Eating citrus fruits more than or equal to 2 times per week could significantly reduce the risk of bladder cancer(P ＜ 0.05). Conclusion Eating more citrus fruits may help reduce the risk of bladder cancer.
凌琦1 吴永定2 秦国强3. 五类常见水果与膀胱癌相关性的多中心病例对照研究[J]. 中国医药导报, 2019, 16(6): 45-48.
LING Qi1 WU Yongding2 QIN Guoqiang3. A multicenter case-control study on the association between five categories of common fruits and bladder cancer. 中国医药导报, 2019, 16(6): 45-48.
[1] Huang L，Kong Q，Liu Z，et al. The Diagnostic Value of MR Imaging in Differentiating T Staging of Bladder Cancer：A Meta-Analysis [J]. Radiology，2018，286（2）：502-511.
[2] Gandhi N，Krishna S，Booth CM，et al. Diagnostic accuracy of magnetic resonance imaging for tumour staging of bladder cancer：systematic review and meta-analysis [J]. BJU Int，2018. [Epub ahead of print]
[3] van Rhijn BW，Burger M，Lotan Y，et al. Recurrence and progression of disease in non-muscle-invasive bladder cancer：from epidemiology to treatment strategy [J]. Eur Urol，2009，56（3）：430-442.
[4] van den Bosch S，Alfred Witjes J. Long-term cancer-specific survival in patients with high-risk，non-muscle-invasive bladder cancer and tumour progression：a systematic review [J]. Eur Urol，2011，60（3）：493-500.
[5] Zhong J，Switchenko J，Jegadeesh NK，et al. Comparison of Outcomes in Patients With Muscle-invasive Bladder Cancer Treated With Radical Cystectomy Versus Bladder Preservation [J]. Am J Clin Oncol，2018. [Epub ahead of print]
[6] Williams SB，Shan Y，Jazzar U，et al. Comparing Survival Outcomes and Costs Associated With Radical Cystectomy and Trimodal Therapy for Older Adults With Muscle-Invasive Bladder Cancer [J]. JAMA Surg，2018. [Epub ahead of print]
[7] Mak KS，Smith AB，Eidelman A，et al. Quality of Life in Long-term Survivors of Muscle-Invasive Bladder Cancer [J]. Int J Radiat Oncol Biol Phys，2016，96（5）：1028-1036.
[8] Kulkarni GS，Hermanns T，Wei Y，et al. Propensity Score Analysis of Radical Cystectomy Versus Bladder-Sparing Trimodal Therapy in the Setting of a Multidisciplinary Bladder Cancer Clinic [J]. J Clin Oncol，2017，35（20）：2299-2305.
[9] Abid Z，Cross AJ，Sinha R，et al. Meat，dairy，and cancer [J]. Am J Clin Nutr，2014，100 Suppl 1：386S-393S.
[10] Radosavljevi■ V，Ili■ M，Jankovi■ S，et al. Diet in bladder cancer ethiopathogenesis [J]. Acta Chir Iugosl，2005，52（3）：77-82.
[11] Li F，An SL，Zhou Y，et al. Milk and dairy consumption and risk of bladder cancer：a meta-analysis [J]. Urology，2011，78（6）：1298-1305.
[12] Liu H，Wang XC，Hu GH，et al. Fruit and vegetable consumption and risk of bladder cancer：an updated meta-analysis of observational studies [J]. Eur J Cancer Prev，2015，24（6）：508-516.
[13] Liang S，Lv G，Chen W，et al. Citrus fruit intake and bladder cancer risk：a meta-analysis of observational studies [J]. Int J Food Sci Nutr，2014，65（7）：893-898.
[14] Vieira AR，Vingeliene S，Chan DS，et al. Fruits，vegetables，and bladder cancer risk：a systematic review and meta-analysis [J]. Cancer Med，2015，4（1）：136-146.
[15] Siegel RL，Miller KD，Jemal A. Global cancer statistics，2017 [J]. CA Cancer J Clin，2017，67（1）：7-30.
[16] Marinoni F，Destro F，Selvaggio GGO，et al. Urothelial carcinoma in children：A case series [J]. Bull Cancer，2018，105（6）：556-561.
[17] 郝捷，陈万青.膀胱癌-2012中国肿瘤登记年报[M].北京：军事医学科学出版社，2012：97.
[18] El-Bolkainy MN，Mokhtar NM，Ghoneim MA，et al. The impact of schistosomiasis on the pathology of bladder carcinoma [J]. Cancer，1981，48（12）：2643-2648.
[19] Heyns CF，van der Merwe A. Bladder cancer in Africa [J]. Can J Urol，2008，15（1）：3899-3908.
[20] 韩苏军，张思维，陈万青，等.中国膀胱癌发病现状及流行趋势分析[J].癌症进展，2013，11（1）：89-95.
[21] de Maturana EL，Rava M，Anumudu C，et al. Bladder Cancer Genetic Susceptibility. A Systematic Review [J]. Bladder Cancer，2018，4（2）：215-226.
[22] Barbosa ALA，Vermeulen SHHM，Aben KK，et al. Smoking intensity and bladder cancer aggressiveness at diagnosis [J]. PLoS One，2018，13（3）：e0194039.
[23] Lee HW，Park SH，Weng MW，et al. E-cigarette smoke damages DNA and reduces repair activity in mouse lung，heart，and bladder as well as in human lung and bladder cells [J]. Proc Natl Acad Sci U S A，2018，115（7）：E1560-E1569.
[24] 戴奇山，何慧婵，钟惟德，等.吸烟与中国人膀胱癌相关性的多中心病例对照研究[J].中华医学杂志，2011，91（34）：2407-2410.
[25] 周玉华，秦国强，戴奇山，等.被动吸烟与膀胱癌相关性的多中心病例对照研究[J].新医学，2014，45（5）：300-303.
[26] 何广宁，钟惟德，毕学成，等.膀胱癌发病率与职业因素的多中心病例对照研究[J].中华医学杂志，2012，92（28）：1978-1980.
2019, Vol. 16 
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