Abstract：Hemorrhagic stroke is a common acute and severe illness. The main cause of the disease usually refers to the rupture of vessels in the cerebral parenchyma or circle of willis. Recently, domestic and foreign experts and scholars divide it into many types according to the area of hemorrhage, and they find that the occurence of secondary brain damage will influence the patients prognosis through research and analysis. However, recent studies have found that Toll-like receptor 4 (TLR4) signal transduction pathways are widespread in post-cerebral hemorrhage inflammation, neuronal apoptosis, cerebral vasospasm and hydrocephalus, and we can reduce the incidence of brain injury by inhibiting TLR4 signaling pathways. Therefore, this article reviews the research progress on the effect of TLR4 on brain injury and its treatment after hemorrhagic stroke.
冯宇轩 姚声涛 匡舒蔓 余国清 向成明. Toll样受体4在出血性脑卒中后脑损伤及其治疗中的作用研究进展[J]. 中国医药导报, 2019, 16(3): 22-27.
FENG Yuxuan YAO Shengtao KUANG Shuman YU Guoqing XIANG Chengming. Research progress on the effect of Toll-like receptor 4 on brain injury and its treatment after hemorrhagic stroke. 中国医药导报, 2019, 16(3): 22-27.
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2019, Vol. 16 
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