Abstract:[Abstract] Objective To investigate the occurring sites of anterior cruciate ligament rupture and explore its influencing factors. Methods From October 2004 to August 2015, in People's Hospital of Tangshan City, the clinical data of 78 patients with injury and confirmed by arthroscopic probe substance section ligament complete rupture were selected. The incidence of the occurring upper, middle, lower site of ACL was analyzed. The influence of age, sex, knee injury mechanisms and injury joint position on the fracture site was analyzed by multivariate Logistic regression analysis. Results Three sections of the fracture incidence were 78.21% (61/78), 20.51% (16/78), 1.28% (1/78) (P < 0.05); the probability of patients with different age and different injury mechanism occured ACL upper site probability was different (P < 0.05); gender, lesion side, damage joints were not related to site of ACL (P > 0.05); compared with ≥30 years, those who were <30 years were more prone to ACL on segment fracture, the risk of increased 4.855 times (OR = 4.855, 95%CI: 2.659-9.004, P = 0.000); compared with the non-contact, the risk of rupture of the segment ACL contact occurs rose 10.549 times (OR = 10.549, 95%CI: 5.156-15.266, P = 0.000). Conclusion Nearly three-quarters of ACL occurs on the first segment, about 1/4 occurs in the middle segment and lower segments rarely occurs; cleavage site may influenced by age, injury mechanisms.