Abstract：Objective To investigate the effect of Guanxinning Tablets on hemodialysis patients with blood stasis type chronic renal failure complicated with carotid atherosclerosis. Methods A total of 97 hemodialysis patients with carotid atherosclerosis blood stasis type chronic renal failure complicated with carotid atherosclerosis who received hemodialysis in Lishui Traditional Chinese Medicine Hospital from March 2021 to March 2023 were selected, they were divided into study group (49 cases) and control group (48 cases) by random number table method. Both groups received symptomatic treatment such as antihypertensive and lipid-lowering therapy combined with hemodialysis treatment. On this basis, the observation group was treated with Guanxinning Tablets for a total of 12 weeks. The changes of blood lipid, renal function, and carotid atherosclerotic plaque before and after treatment were compared between the two groups. Results After treatment, the levels of low density lipoprotein cholesterol, total cholesterol, and triglyceride in both groups were lower than before treatment, and study group was lower than control group (P＜0.05). After treatment, the levels of serum creatinine and urea nitrogen in both groups were lower than before treatment, and study group was lower than control group (P＜0.05). The maximum area of carotid atherosclerotic plaque decreased in both groups compared with before treatment, and the study group was smaller than the control group (P＜0.05). Conclusion The application of Guanxinning Tablets can effectively improve the blood lipid level of hemodialysis patients with blood stasis type chronic renal failure complicated with carotid atherosclerosis, and can improve their renal function and reduce carotid atherosclerosis plaque.
2023, Vol. 20 
京公网安备 11010502046598号