Abstract：Objective To investigate the effect of CT-guided puncture combined with urokinase drainage in the treatment of hypertensive cerebral hemorrhage. Methods A total of 90 patients with hypertensive cerebral hemorrhage who received treatment in Xinyi People’s Hospital of Jiangsu Province from October 2020 to October 2022 were selected, and they were divided into experimental group (CT-guided puncture combined with urokinase drainage treatment, 45 cases) and control group (urokinase drainage, 45 cases) by random number table method. The treatment effect and survival rate of one, three, and six months after treatment were compared between two groups; the levels of serum myelin basic protein (MBP) and serum ferritin (SF) were compared between two groups before treatment and three months after treatment; operation time, intraoperative blood loss, hematoma before and after operation, and postoperative bed time were compared between two groups; the occurrence of complications in two groups was recorded. Results There was no significant difference in treatment effect between two groups (P＞0.05); there were no significant differences in survival rates at one, three, and six months after treatment between two groups (P＞0.05). At three months after treatment, the levels of MBP and SF in both groups were lower than those before treatment, and experimental group was lower than control group (P＜0.05). The operative time and postoperative bed time of experimental group were shorter than those of control group, intraoperative blood loss was lower than that of control group, and the difference of hematoma before and after operation was greater than that of control group (P＜0.05). The total incidence of adverse reactions in experimental group was lower than that in control group (P＜0.05). Conclusion Both CT-guided puncture combined with urokinase drainage and urokinase drainage alone are effective in the treatment of hypertensive cerebral hemorrhage. CT-guided puncture combined with urokinase drainage is better than urokinase drainage alone in postoperative complications and neurological rehabilitation.
晁先礼 张 明 项朝晖. CT引导穿刺联合尿激酶引流治疗高血压脑出血效果比较[J]. 中国医药导报, 2023, 20(35): 102-105.
CHAO Xianli ZHANG Ming XIANG Zhaohui. Comparison of the effect of CT-guided puncture combined with urokinase drainage in the treatment of hypertensive cerebral hemorrhage. 中国医药导报, 2023, 20(35): 102-105.
2023, Vol. 20 
京公网安备 11010502046598号