Abstract：Objective To explore the clinical characteristics of measles complicated with pneumonia in children and to provide reference for the diagnosis and treatment of children with measles. Methods A retrospective study was conducted to collect the clinical data, including demographic data, measles infection, and laboratory results, of 0-18 year old children with measles who were first diagnosed with measles in Beijing Youan Hospital, Capital Medical University from June 2010 to June 2022. The children were divided into pneumonia group and non-pneumonia group according to whether they were complicated with pneumonia. The clinical data were analyzed and summarized. Results Among 671 children with measles, a total of 601 cases were complicated with pneumonia, most of them were male, and few complications were complicated. The clinical manifestations were fever, cough, and rash. The age of onset in the pneumonia group was lower than that in the non-pneumonia group, and the proportion of previous history was higher than that in the non-pneumonia group, and the differences were statistically significant (P＜0.05). There were significant differences in the proportion of cough, Collinia spot, total complication rate, and gastroenteritis between the two groups (P＜0.05). The median indexes of white blood cell count, neutrophil count, C-reactive protein, and creatinine in pneumonia group were higher than those in non-pneumonia group, and the differences were statistically significant (P＜0.05). The proportion of antibiotics used in pneumonia group was higher than that in non-pneumonia group, and the difference was statistically significant (P＜0.05). The proportion of antiviral drugs used in pneumonia group was lower than that in non-pneumonia group, and the difference was statistically significant (P＜0.05). The hospitalization days in the pneumonia group were longer than that in the non-pneumonia group, and the difference was statistically significant (P＜0.05). Conclusion Pneumonia is the main complication of measles, and the clinical manifestations of children with measles comp- licated with pneumonia are more serious than those without measles complicated with pneumonia. Understanding the clinical manifestations and laboratory examination results of measles complicated with pneumonia is helpful to judge the prognosis and provide guidance for correct treatment.
王 禹 王斯同 蔡妙甜 张志丽 张玉林. 儿童麻疹合并肺炎的临床特征分析[J]. 中国医药导报, 2023, 20(35): 70-73.
WANG Yu WANG Sitong CAI Miaotian ZHANG Zhili ZHANG Yulin. Analysis of clinical features of measles complicated with pneumonia in children. 中国医药导报, 2023, 20(35): 70-73.
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