Influencing factors of postoperative complications in patients with radical hysterectomy for cervical cancer
ZHANG Shanshan PENG Yan XIANG Rui WANG Jingyi
Department of Obstetrics and Gynecology, the Second Affiliated Hospital of Chengdu Medical College Nuclear Industry 416 Hospital, Sichuan Province, Chengdu 610051, China
Abstract：Objective To analyze the influencing factors of postoperative complications in patients with radical hysterectomy for cervical cancer (CC). Methods The clinical data of 379 patients who received radical hysterectomy for CC in the Second Affiliated Hospital of Chengdu Medical College Nuclear Industry 416 Hospital from January 2020 to March 2023 were retrospectively collected. According to whether postoperative complications occurred, the patients were divided into complication group and non-complication group. The influencing factors of complications after radical hysterectomy for CC were analyzed. Results The complication rate of 379 patients after radical hysterectomy for CC was 20.32% (77/379). There were no significant differences in age, diabetes mellitus, hypertension, education background, family annual income, menopause, history of pelvic surgery, pathological classification, length of vaginal resection, length of principal ligament resection, and the levels of squamous cell carcinoma antigen and carbohydrate antigen 125 between two groups (P＞0.05); there were significant differences in body mass index (BMI), tumor diameter, clinical stage, lymph node metastasis, number of lymph node dissection, lymph vessel ligation, operation time, intraoperative blood loss, hemoglobin (Hb), serum albumin, C-reactive protein (CRP), and complement C3 between two groups (P＜0.05). BMI (OR=2.675), clinical stage (OR=3.350), lymph node metastasis (OR=3.010), number of lymph node dissection (OR=2.568), operation time (OR=2.442), and CRP (OR=3.093) were the risk factors for complications after radical hysterectomy for CC (P＜0.05); lymphatic vessel ligation was a protective factor for complications after radical hysterectomy for CC (OR=0.310, P＜0.05). Conclusion The main complications after radical hysterectomy for CC are urinary retention, ureteral fistula, and postoperative incision infection. BMI, clinical stage, lymph node metastasis, number of lymph node dissection, operation time, CRP are risk factors, lymph vessel ligation were protective factors. Therefore, clinical treatment or intervention can be given to reduce the risk of postoperative complications for patients.
2023, Vol. 20 
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