中国医药导报
中国医药期刊欢迎您 今天是   2025年4月4日星期五
设为首页 | 加入收藏 
 
        首 页      期刊介绍      下载中心      关于本刊      投稿指南      期刊订阅      在线留言      广告合作      联系我们      返回中国当代医药网
中国医药导报  2023, Vol. 20 Issue (33): 100-103    DOI: 10.20047/j.issn1673-7210.2023.33.22
  临床医学-内分泌 本期目录 | 过刊浏览 | 高级检索 |
体重指数正常的2型糖尿病患者内脏脂肪面积与心脑血管并发症的关系
项晓燕1  叶娟2▲
1.上海交通大学医学院苏州九龙医院内分泌科,江苏苏州 215028;
2.上海交通大学医学院苏州九龙医院医学影像科,江苏苏州 215028
Relationship between visceral fat area and cardiovascular and cerebrovascular complications in type 2 diabetes mellitus patients with normal body mass index
XIANG Xiaoyan1 YE Juan2▲
1.Department of Endocrinology, Suzhou Jiulong Hospital, School of Medicine, Shanghai Jiao Tong University, Jiangsu Province, Suzhou 215028, China;
2.Department of Medical Imaging, Suzhou Jiulong Hospital, School of Medicine, Shanghai Jiao Tong University, Jiangsu Province, Suzhou 215028, China
全文: PDF (586 KB)   HTML (1 KB) 
输出: BibTeX | EndNote (RIS)      
摘要 目的 探讨体重指数(BMI)正常的2型糖尿病患者内脏脂肪面积与心脑血管并发症的关系。 方法 选取2018年1月至2021年5月在上海交通大学医学院苏州九龙医院治疗的BMI正常的2型糖尿病合并心脑血管并发症患者44例作为观察组(其中合并冠心病24例、脑梗死20例),同时选取BMI正常的单纯2型糖尿病患者132例作为对照组。比较两组内脏脂肪面积、空腹血糖(FPG)、空腹胰岛素(FINS)、胰岛素抵抗指数(HOMA-IR)等差异,并绘制受试者操作特征(ROC)曲线分析内脏脂肪面积对BMI正常的2型糖尿病患者合并心脑血管疾病的诊断价值。 结果 两组糖尿病病程和吸烟比例、内脏脂肪面积、FPG、FINS和HOMA-IR比较,差异有统计学意义(P<0.05)。logistic回归分析显示:糖尿病病程(OR=2.440,95%CI:1.483~4.014)、吸烟(OR=3.013,95%CI:1.730~ 5.247)、内脏脂肪面积(OR=2.250,95%CI:1.459~3.470)是患者合并心脑血管并发症发生的影响因素(P<0.05),该方程ROC曲线下面积为0.820(95%CI:0.746~0.894,P<0.05),灵敏度和特异度分别为75.00%和78.00%。结论 BMI正常的2型糖尿病合并心脑血管并发症患者内脏脂肪面积增加,对该病具有一定的诊断价值。
服务
把本文推荐给朋友
加入我的书架
加入引用管理器
E-mail Alert
RSS
作者相关文章
项晓燕1  叶娟2▲
关键词 体重指数2型糖尿病内脏脂肪面积心脑血管并发症    
Abstract:Objective To investigate the relationship between visceral fat area and cardiovascular and cerebrovascular complications in type 2 diabetes mellitus patients with normal body mass index (BMI). Methods From January 2018 to May 2021, 44 patients with type 2 diabetes mellitus and cardiovascular and cerebrovascular complications (24 cases of combined coronary heart disease and 20 cases of cerebral infarction)with normal BMI who were treated in Suzhou Jiulong Hospital, School of Medicine, Shanghai Jiao Tong University were selected as the observation group, and 132 patients with simple type 2 diabetes mellitus with normal BMI were selected as the control group. The differences in visceral fat area, fasting glucose (FPG), fasting insulin (FINS), insulin resistance index (HOMA-IR), etc. between the two groups were compared, and the receiver operating characteristic (ROC) curve was drawn to analyze the diagnostic value of visceral fat area for type 2 diabetes mellitus patients with normal BMI complicated with cardiovascular and cerebrovascular diseases. Results There were significant differences in diabetes course, smoking proportion, visceral fat area, FPG, FINS and HOMA-IR between the two groups (P<0.05). Logistic regression analysis showed that the course of diabetes (OR=2.440, 95%CI:1.483-4.014), smoking [OR=3.013, 95% CI:1.730-5.247), visceral fat area [OR=2.250, 95%CI:1.459-3.470) were the influencing factors of patients with cardiovascular and cerebrovascular complications (P<0.05), the area under the ROC curve of this equation was 0.820 (95%CI:0.746-0.894, P<0.05), sensitivity and specificity were 75.00% and 78.00%, respectively. Conclusion The visceral fat area of type 2 diabetes mellitus patients with normal BMI and cardiovascular and cerebrovascular complications increases, which has certain diagnostic value for the disease.
Key wordsBody mass index    Type 2 diabetes mellitus    Visceral fat area    Cardiovascular and cerebrovascular complications
    
基金资助:江苏省自然科学基金项目(BK20200209);
江苏省苏州市科技计划项目(SZM2021024)。
通讯作者: ▲通讯作者   
作者简介: 项晓燕(1986.10-),女,硕士;研究方向:糖尿病与肥胖。
引用本文:   
项晓燕1  叶娟2▲. 体重指数正常的2型糖尿病患者内脏脂肪面积与心脑血管并发症的关系[J]. 中国医药导报, 2023, 20(33): 100-103.
XIANG Xiaoyan1 YE Juan2▲. Relationship between visceral fat area and cardiovascular and cerebrovascular complications in type 2 diabetes mellitus patients with normal body mass index. 中国医药导报, 2023, 20(33): 100-103.
链接本文:  
https://www.yiyaodaobao.com.cn/CN/10.20047/j.issn1673-7210.2023.33.22     或     https://www.yiyaodaobao.com.cn/CN/Y2023/V20/I33/100

 

中华人民共和国互联网药品信息服务资格证书(京)-非经营性-2016-0092
京ICP11001767号-2  京公网安备 11010502046598号  期刊出版许可证 广告经营许可证
信息产业部备案管理系统网址 http://beian.miit.gov.cn/state/outPortal/loginPortal.action
投稿热线:010-59626203
本刊地址:北京市朝阳区东四环中路78号楼(大成国际中心B1座)8B02室 邮编:100124
传真:010-59626204 投稿信箱:ddyy@vip.163.com
版权所有:中文传媒集团北京期刊有限公司
技术支持:北京玛格泰克科技发展有限公司