Analysis of influencing factors of atherosclerosis in type 2 diabetes mellitus
WU Li1 ZHU Hong1 CAO Changchun1 MA Jian2 LI Qian3 YE Meng3 ZHOU Wen1 WANG Shuang1
1.Department of Endocrinology, Nanjing Drum Tower Hospital Group Suqian Hospital the Affiliated Suqian Hospital of Xuzhou Medical University, Jiangsu Province, Suqian 223800, China; 2.Department of Ultrasonic Diagnosis, Nanjing Drum Tower Hospital Group Suqian Hospital the Affiliated Suqian Hospital of Xuzhou Medical University, Jiangsu Province, Suqian 223800, China; 3.Department of Clinical Nutrition, Nanjing Drum Tower Hospital Group Suqian Hospital, the Affiliated Suqian Hospital of Xuzhou Medical University, Jiangsu Province, Suqian 223800, China
Abstract：Objective To explore the influencing factors of arteriosclerosis (AS) in type 2 diabetes mellitus (T2DM) patients. Methods A total of 120 patients with T2DM who were hospitalized in Department of Endocrinology, Nanjing Drum Tower Hospital Group Suqian Hospital from July 2019 to September 2021 were selected, and divided into arteriosclerosis group (60 cases) and non-atherosclerosis group (60 cases) according to the color doppler ultrasound results. The general clinical data of the two groups were compared; and the risk factors of AS were analyzed by logistic regression; receiver operating characteristic (ROC) curve was used to analyse the ability of visceral fat area (VFA) to predict AS risk. Results There were significant differences in age, systolic blood pressure, body mass index, VFA, total cholesterol, triglyceride, low density lipoprotein cholesterol, fasting blood glucose, steady-state model insulin resistance index, diabetic microanglopathy, and hypertension between the two groups (P＜0.05). Logistic regression analysis showed that VFA, age and triglyceride were independent risk factors for AS in T2DM patients (P＜0.05). ROC curve showed that the area under the curve of VFA in predicting AS in T2DM patients was 0.702, the critical value was 114.7 cm2, the sensitivity was 0.617, and the specificity was 0.733. Conclusion Increased VFA, especially VFA＞114.7 cm2 is closely related to the occurrence of AS in T2DM patients.
吴利1 朱红1 曹长春1 马建2 李茜3 叶梦3 周文1 王双1. 2型糖尿病发生动脉硬化的影响因素分析[J]. 中国医药导报, 2023, 20(33): 96-99.
WU Li1 ZHU Hong1 CAO Changchun1 MA Jian2 LI Qian3 YE Meng3 ZHOU Wen1 WANG Shuang1. Analysis of influencing factors of atherosclerosis in type 2 diabetes mellitus. 中国医药导报, 2023, 20(33): 96-99.
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2023, Vol. 20 
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