Meta analysis of the clinical value of preservation of pelvic autonomic nervous system in total mesorectal resection surgery for middle and low rectal cancer
LAI Suyu ZHAO Ziting REN Bing ZENG Yixian RUAN Mengyi WANG Xiaofeng
Department of Anorectal, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100032, China
Abstract：Objective To evaluate the clinical value of preservation of pelvic autonomic nervous system in middle and low rectal cancer during total mesorectal resection. Methods Using RevMan 5.4 software, CNKI, VIP, Wanfang Database, SinoMed, Cochrane Library, PubMed, EMbase database, and Web of Science database were searched, randomized controlled trial (RCT) screening for pelvic autonomic nerve sparing treatment of middle and low rectal cancer during total mesorectal resection. The retrieval period was from the establishment of the database to April 2023. Meta-analysis was performed using RevMan 5.4 software. Results Finally, ten RCTs were included, including 899 patients. Data showed that the incidence of postoperative erectile dysfunction in the observation group was lower than that in the control group [RR= 0.46, 95%CI (0.38-0.58), P＜0.000 01], the incidence of postoperative ejaculatory dysfunction in the observation group was lower than that in the control group [RR=0.54, 95%CI (0.46, 0.65), P＜0.000 01], the effect of postoperative urination function in the observation group was lower than that in the control group [RR=0.38，95%CI (0.29-0.51), P＜0.000 01]; there was no significant difference in tumor recurrence rate between the two groups [RR=0.82, 95%CI (0.45-1.52), P=0.53]. Conclusion In the surgical treatment of middle and low rectal cancer, compared with traditional radical rectal cancer surgery, although total mesorectal excision +pelvic autonomic nerve preservation did not significantly improve the recurrence rate, it could protect postoperative sexual function and urination and improve the quality of life, which has clinical value.
赖素玉 赵姿婷 任冰 曾译贤 阮梦怡 王晓锋. 中低位直肠癌全直肠系膜切除手术中保留盆腔自主神经临床价值的meta分析[J]. 中国医药导报, 2023, 20(32): 112-116.
LAI Suyu ZHAO Ziting REN Bing ZENG Yixian RUAN Mengyi WANG Xiaofeng. Meta analysis of the clinical value of preservation of pelvic autonomic nervous system in total mesorectal resection surgery for middle and low rectal cancer. 中国医药导报, 2023, 20(32): 112-116.
2023, Vol. 20 
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