Abstract:Objective To explore the clinical effect of xingnao kaiqiao acupuncture combined with repetitive transcranial magnetic stimulation (rTMS) in the treatment of post stroke thalamic pain (PSTP). Methods A total of 198 patients with PSTP admitted to Liaoning Jinqiu Hospital from September 2018 to October 2022 were selected and they were divided into three groups according to random number table method, with 66 cases in each group. Control group 1 received rTMS treatment, control group 2 received xingnao kaiqiao acupuncture treatment, and combined group received xingnao kaiqiao acupuncture combined with rTMS treatment, all three groups were treated for six weeks. The clinical efficacy, pain degree, inflammatory factor level, and safety of the three groups after treatment were compared. Results The clinical effect of combined group was better than control group 1 and control group 2, and the difference was statistically significant the difference was statistically significant (P<0.05). After treatment, visual analogue scale score, current pain intensity score and pain grading index score of the three groups were lower than those before treatment, and the combined group were lower than control group 1 and control group 2; serum levels of interleukin-6 and tumor necrosis factor-α in three groups were lower than those before treatment, and the combined group were lower than control group 1 and control group 2, the differences were statistically significant (P<0.05). No significant adverse reactions were observed during the treatment of the three groups. Conclusion The clinical efficacy of xingnao kaiqiao acupuncture combined with rTMS in the treatment of PSTP is definite, which can significantly alleviate pain symptoms and reduce serum inflammatory factor levels.