Effects of perioperative period thermal insulation intervention on stress response and complications in patients undergoing thoracoscopic lung surgery under general anesthesia
WANG Yan YAN Li ZHANG Jianmei ZHONG Zhaoping
Department of Surgery Anesthesiology, Huaian First People’s Hospital, Jiangsu Province, Huaian 223300, China
Abstract:Objective To investigate the effects of perioperative period thermal insulation intervention on stress response and complications in patients undergoing thoracoscopic lung surgery under general anesthesia. Methods A total of 110 patients with thoracoscopic lung surgery treated in Huaian First People’s Hospital, Jiangsu Province from October 2019 to November 2022 were selected as the study objects, and they were divided into control group (55 cases) and observation group (55 cases) by random number table method. The control group received routine intervention in perioperative period, and the observation group received thermal insulation intervention in perioperative period on the basis of control group. Both groups were observed until the patients left the anesthesia recovery room. The body temperature between two groups was compared before anesthesia (T0), 60 min after the operation (T1), at the end of operation (T2), immediately after entering the anesthesia recovery room (T3), 15 min after entering the anesthesia recovery room (T4), and at the exit of the anesthesia recovery room (T5); the levels of norepinephrine (NE), epinephrine (E), and cortisol (Cor) at T0, T2, and T4 were compared between two groups; the occurrence of complications in two groups was observed. Results Overall comparison: there were statistically significant differences in body temperature time, inter-group, and interaction between two groups (P<0.05). Intra-group comparison: compared with T0, the body temperature of control group decreased at T1; compared with T1, the body temperature was increased at T2-T5, and the differences were statistically significant (P<0.05). Compared with T0, the body temperature of observation group was increased at T2-T5, and the differences were statistically significant (P<0.05). Comparison between groups: the body temperature of observation group at T1-T5 was higher than that of control group, and the difference was statistically significant (P<0.05). Overall comparison: there were statistically significant differences in the levels of NE, E, and Cor time, inter-group, and interaction between two groups (P<0.05). Intra-group comparison: the pairwise comparison of the levels of NE, E, and Cor in two groups at different time points had statistical significance (P<0.05). Comparison between groups: the levels of NE, E and Cor at T2, T4 in observation group were lower than those in control group, and the differences were statistically significant (P<0.05). The total incidence of complications in observation group was lower than that in control group, and the difference was statistically significant (P<0.05). Conclusion Perioperative thermal insulation intervention could help maintain the body temperature of patients undergoing thoracoscopic lung surgery, reduce the stress response, postoperative complications of patients, and had a good intervention effect.
王艳 阎莉 张建梅 仲兆萍. 围手术期保温干预对全身麻醉胸腔镜肺手术患者应激反应及并发症的影响[J]. 中国医药导报, 2023, 20(31): 119-123.
WANG Yan YAN Li ZHANG Jianmei ZHONG Zhaoping. Effects of perioperative period thermal insulation intervention on stress response and complications in patients undergoing thoracoscopic lung surgery under general anesthesia. 中国医药导报, 2023, 20(31): 119-123.