Abstract:Objective To study the abnormal bone mass of cadres in Xinjiang Uygur Autonomous Region who underwent physical examination in the People’s Hospital of Xinjiang Uygur Autonomous Region, and to analyze its risk factors, so as to provide reference for the prevention and treatment of osteoporosis. Methods A total of 1 102 cadres from the district offices who underwent physical examination in the People’s Hospital of Xinjiang Uygur Autonomous Region from January 2020 to December 2021 were selected as the study subjects. The age, sex, and chronic diseases of the subjects were investigated by questionnaire. Physical examination and bone density examination were performed on the subjects. The subjects were divided into three groups according to bone mineral density examination: normal bone mass group (861 subjects), bone loss group (109 subjects), osteoporosis group (132 subjects); logistic regression was used to analyze the risk factors of abnormal bone mass. Results The total prevalence of osteopenia was 9.89%, while the total prevalence of osteoporosis was 11.98%. There were significant differences in gender distribution, age, low density lipoprotein cholesterol (LDL-C), 25- hydroxyvitamin D[25 (OH) D] among the three groups (P<0.05). Logistic regression analysis showed that 25 (OH) D was a protective factor for bone loss (OR [95%CI] =0.920 [0.888-0.953], P<0.05), LDL-C was a risk factor for bone loss (OR [95%CI] =1.431 [1.116- 1.835], P<0.05); age (OR [95%CI] =1.075 [1.053-1.098], P<0.05), LDL-C(OR [95%CI] =1.334 [1.054-1.689], P<0.05) were risk factors for osteoporosis. 25 (OH) D (OR [95%CI] =0.914 [0.883-0.946], P<0.05) and male (OR [95%CI] =0.302 [0.160- 0.570], P<0.05) were protective factors for osteoporosis. Conclusion The prevalence rate of osteoporosis of cadres aged 50 and above in the district offices is high, so pay attention to health examination.
杨英1 王庆2▲. 基于健康体检研究新疆区直机关干部骨量异常的影响因素[J]. 中国医药导报, 2023, 20(30): 76-80,112.
YANG Ying1 WANG Qing2▲. Analysis of influencing factors of abnormal bone mass of Cadres of organs directly under Xinjiang Uygur Autonomous Region. 中国医药导报, 2023, 20(30): 76-80,112.