Abstract:Objective To compare the diagnostic efficiency of contrast-enhanced ultrasound and MRI-diffusion weighted imaging (DWI) in benign and malignant soft tissue tumors. Methods The clinical data of 189 patients with soft tissue tumors who received diagnosis and treatment in Shijiazhuang People’s Hospital from December 2020 to November 2021 were retrospectively analyzed. All patients underwent contrast-enhanced ultrasound and MRI-DWI examination before surgery. The diagnostic efficiency of contrast-enhanced ultrasound and MRI-DWI in benign and malignant soft tissue tumors was analyzed with pathological results as the gold standard; the apparent diffusion coefficient (ADC) and relative apparent diffusion coefficient (rADC) of benign and malignant soft tissue tumors were compared, and the correlation between the properties of soft tissue tumors and ADC and rADC was analyzed. Results Among 189 patients, 62 were malignant soft tissue tumors. The sensitivity, specificity, and accuracy of contrast-enhanced ultrasound in the diagnosis of malignant soft tissue tumor were 77.42%, 74.02%, and 75.13%; the sensitivity, specificity, and accuracy of MRI-DWI in the diagnosis of malignant soft tissue tumors were 88.71%, 97.64%, and 94.71%. ADC and rADC in benign soft tissue tumors were higher than those in malignant soft tissue tumors (P<0.05). The properties of soft tissue tumors (benign=0, maliganant=1) were negatively correlated with ADC and rADC (r<0, P<0.05). Conclusion The diagnostic efficiency of mRI-DWI in the diagnosis of benign and malignant soft tissue tumors is higher than that of contrast-enhanced ultrasound, which can provide more reliable and effective objective data reference for clinical diagnosis.