Effect of upper limb compression therapy on the prevention of peripherally inserted central venous catheter related thrombosis in patients with inability to exercise
XU Suiyun1 WANG Wenxu2 HAN Yan1 GAO Yang1 GUO Lei1 YAN Xianxia1
1.Department of Neurosurgery, the Second Affiliated Hospital of Xi’an Jiaotong University, Shaanxi Province, Xi’an 710004, China;
2.Precision Medical Research Institute, the Second Affiliated Hospital of Xi’an Jiaotong University, Shaanxi Province, Xi’an 710004, China
Abstract：Objective To observe the effect of upper limb compression therapy on the prevention of peripherally inserted central venous catheter (PICC) related thrombosis in patients with inability to exercise. Methods A total of 84 patients with inability to exercise underwent upper limb PICC catheterization and catheter maintenance in the Second Affiliated Hospital of Xi’an Jiaotong University from January 2020 to August 2022 were selected. They were divided into control group and compression group by random number table method, with 42 cases in each group. The control group was given passive activity intervention, and the compression group was given air pressure wave intervention. Color Doppler ultrasound was used to monitor the blood flow velocity of axillary vein and subclavian vein before intervention and 30 minutes after intervention in the two groups. The levels of fibrinogen, prothrombin time, and D-dimer were measured before catheterization and two weeks after catheterization. The incidence of PICC related thrombosis in the two groups was recorded. Results After 30 minutes of intervention, the blood flow velocity of axillary vein and subclavian vein in the two groups were faster than those before intervention, and that in the compression group was faster than that in the control group, and the differences were statistically significant (P＜0.05). After two weeks of catheterization, the levels of fibrinogen, prothrombin time, and D-dimer in the control group were higher than those before catheterization, and higher than those in the compression group, and the differences were statistically significant (P＜0.05). There were no significant differences in fibrinogen, prothrombin time, and D-dimer before and two weeks after catheterization in the compression group (P＞0.05). During the observation period of two weeks, the incidence of PICC related thrombosis in the compression group was lower than that in the control group, and the difference was statistically significant (P＜0.05). Conclusion Air pressure wave therapeutic instrument can effectively prevent upper extremity PICC related thrombosis in patients without exercise ability by increasing the venous blood flow velocity on the catheterization side.
徐岁云1 王文旭2 韩艳1 高炀1 郭磊1 闫先侠1. 上肢加压治疗在预防无运动能力患者经外周静脉穿刺的中心静脉导管相关血栓形成中的作用[J]. 中国医药导报, 2023, 20(23): 135-138,181.
XU Suiyun1 WANG Wenxu2 HAN Yan1 GAO Yang1 GUO Lei1 YAN Xianxia1. Effect of upper limb compression therapy on the prevention of peripherally inserted central venous catheter related thrombosis in patients with inability to exercise. 中国医药导报, 2023, 20(23): 135-138,181.
[1] Santos FKY，Flumignan RLG，Areias LL，et al. Peripherally inserted central catheter versus central venous catheter for intravenous access：A protocol for systematic review and meta-analysis [J]. Medicine（Baltimore），2020，99（30）：e20352.
[2] 惠慧，马燕兰，郭梅，等.恶性肿瘤病人PICC相关性血栓风险因素及护理干预研究进展[J].护理研究，2019，33（5）：811-816.
[3] 李杰萍，姜翠红，管树荣，等.PICC相关性静脉血栓的危险因素及预防措施的研究进展[J].护士进修杂志，2019， 34（10）：886-889.
[4] 赵玲玲，陈英，杨茜，等.间歇充气加压预防妇科手术患者深静脉血栓的Meta分析[J].护理管理杂志，2021，21（8）： 543-548.
[5] 吴冰，吴青，李瑞华，等.快速康复训练联合空气压力波对乳腺癌术后患者上肢功能的影响[J].癌症进展，2022， 20（10）：1031-1034.
[6] 陈章霞，梁凤娟，朱泳仪.空气压力波在预防高危孕产妇产后下肢深静脉血栓形成的应用[J].实用医学杂志，2021， 37（16）：2119-2123.
[7] 金琳，许阳子，王希成，等.空气波压力治疗仪预防PICC相关血栓的效果观察[J].护理研究，2015（29）：952-953.
[8] 朱敏，姜敏，刘晓晖，等.彩色多普勒超声在自然分娩、剖宫产后并发下肢深静脉血栓形成的诊断价值[J].血栓与止血学，2019，25（4）：679-680.
[9] 陆再英，钟南山.内科学[M].北京：人民卫生出版社，2011：358.
[10] 丁明艳，倪苗苗，韩哲洙，等.肿瘤患者中心静脉导管相关性血栓形成与炎症指标的关系[J].中国医药科学，2022，12（22）：126-130.
[11] Pan L，Zhao Q，Yang X. Risk factors for venous thrombosis associated with peripherally inserted central venous cath- eters [J]. Int J Clin Exp Med，2014，7（12）：5814-5819.
[12] 王宁，郭振江，张媛媛，等.利伐沙班与低分子肝素治疗中心静脉置入设备相关性上肢深静脉血栓的疗效比较[J].天津医药，2021，49（4）：432-435.
[13] 刘花，王咏梅，黄薇薇.上下肢深静脉血栓患者的临床特征对比[J].中国实验诊断学，2021，25（2）：223-227.
[14] 褚达明，刘藤藤，栾南南.自制心电定位系统及利伐沙班对卵巢癌患者经外周置入中心静脉导管相关深静脉血栓的预防效果[J].中国药物与临床，2021，21（4）：572-575.
[15] 胡佳丽，项丽婷，戚红萍，等.肿瘤化疗患者PICC相关性上肢静脉血栓形成时间及其影响因素分析[J].中国现代医学杂志，2021，31（6）：51-57.
[16] Chen P，Zhu B，Wan G，et al. The incidence of asymptomatic thrombosis related to peripherally inserted central catheter in adults：A systematic review and meta-analysis People’s [J]. Nurs Open，2021，8（5）：2249-2261.
[17] Liu B，Wu Z，Lin C，et al. Applicability of TIVAP versus PICC in non-hematological malignancies patients：A meta- analysis and systematic review [J]. PLoS One，2021，16（8）：e0255473.
[18] Luo H，Jin C，Li X，et al. Quantified versus willful handgrip exercises for the prevention of PICC-related thrombosis：A meta-analysis and systematic review [J].Medicine（Baltimore），2023，102（10）：e32706.
[19] 王宏香，王天晓，杨春华，等.系统护理联合气压治疗预防多发性骨折患者下肢深静脉血栓的价值[J].现代中西医结合杂志，2022，31（22）：3179-3182.
[20] 李苓，毋涛，张永华，等.间歇充气加压联合运动训练预防肺癌患者PICC后DVT风险的价值[J].中华保健医学杂志，2022，24（3）：179-181.
[21] 于晓洁.空气压力波治疗仪在下肢骨折患者静脉血栓中的预防效果[J].现代科学仪器，2021，38（3）：128-132.
[22] 潘玉琴，陶婷，吴晔.空气压力波治疗仪联合体感诱发电位监测预防脊柱骨折术后下肢深静脉血栓形成的应用效果[J].中国医学物理学杂志，2021，38（12）：1554- 1559.
[23] 赵娟，孙迎红，李卫峰，等.成人恶性肿瘤患者PICC血栓预防的最佳证据总结[J].护士进修杂志，2020，35（13）：1197-1202.
[24] 邱楚瑾，宋雨晴，蒋艳.间歇性气压治疗对乳腺癌相关淋巴水肿干预效果的Meta分析[J].中国护理管理，2022， 22（2）：261-267.
[25] 李雪娇，王健，皮红英.上肢加压对经外周置入中心静脉导管患者血流动力学影响的研究[J].解放军护理杂志，2018，35（18）：46-49.
[26] Lin L，Liang Z，Li Z，et al. Effect of plan-do-check-active method combined with air pressure wave therapy on the prevention of deep venous thrombosis in critically ill patients in neurosurgery [J]. Ann Palliat Med，2023，12（1）：103-110.
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