Influence of diabetes mellitus on lower urinary tract symptoms in middle-aged and elderly men
ZHANG Songwei1 WANG Fucheng1 ZHANG Huiqing1 WEN Jianguo2
1.Department of UrologySurgery, the First Affiliated Hospital of Xinxiang Medical University, Henan Province, Weihui 453100, China;
2.Department of Urology Surgery, the First Affiliated Hospital of Zhengzhou University, Henan Province, Zhengzhou 450052, China
Abstract:Objective To investigate the influence of diabetes mellitus on lower urinary tract symptoms in middle-aged and elderly men. Methods A total of 252 middle-aged and elderly male patients admitted to the First Affiliated Hospital of Xinxiang Medical University for lower urinary tract symptoms from December 2021 to March 2022 were selected as the study objects, and were divided into diabetes mellitus group (83 cases) and non-diabetes mellitus group (169 cases) according to whether they had diabetes mellitus. The international prostate symptom score (IPSS), health-related quality of life (HRQL) questionnaire, free urine flow rate examination, and residual urine volume (RUV) measurement were performed between the two groups. The differences of each scale score between the two groups were compared, and the differences of each scale score between the different disease course (≥ five years, 55 cases; < five years, 28 cases) and fasting plasma glucose (FPG) (>10.0 mmol/L, 38 cases; ≤10.0 mmol/L, 45 cases) in diabetes mellitus group were compared. Results The maximum urine flow rate and average urine flow rate in the diabetes mellitus group were lower than those in the non-diabetes mellitus group, and the scores of IPSS, HRQL questionnaire, and urinary storage period were higher than those in the non-diabetes mellitus group, the differences were statistically significant (P<0.05). The urine storage period score and HRQL questionnaire score of diabetic patients with disease course≥ five years were lower than those of patients with disease course < five years, and the differences were statistically significant (P<0.05). The average urine flow rate of diabetic patients with FPG>10.0 mmol/L was higher than that of patients with FPG≤10.0 mmol/L, and the difference was statistically significant (P<0.05). Conclusion In middle-aged and elderly men with diabetes, lower urinary tract symptoms are more severe, and their quality of life is also reduced.