Correlation of Wanger grade with hematocrit, albumin, difference of hematocrit and albumin in patients with type 2 diabetes mellitus complicated with diabetic foot
SHANG Junliang WANG Guangyu SHI Chunhong XU Xuying
Department of Sore and Ulcer Vascular Surgery, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China
Abstract:Objective To investigate the correlation of Wanger grade with hematocrit (HCT), albumin (ALB), difference of HCT and ALB (|HCT-ALB|) in patients with type 2 diabetes mellitus complicated with diabetic foot. Methods A retrospective analysis was performed on 90 patients with type 2 diabetes mellitus complicated with diabetic foot admitted to Beijing Hospital of Traditional Chinese Medicine, Capital Medical University from January 2019 to January 2020, and they were divided into Wagner 1 group (30 cases), Wagner 2-3 group (25 cases), and Wagner 4-5 group (35 cases) according to Wanger grade. Clinical data of the three groups were compared. The correlation between serum levels of HCT, ALB, |HCT-ALB|, and Wanger grade were analyzed. Results The age and duration of type 2 diabetes mellitus in Wagner 2-3 and Wagner 4-5 groups were higher than those in Wagner 1 group, and the differences were statistically significant (P<0.05). The levels of sodium, hemoglobin, HCT, and ALB in Wagner 4-5 group were lower than those in Wagner1 and Wagner 2-3 groups, and the levels of white blood cell count and C-reactive protein were higher than those in Wagner1 and Wagner 2-3 groups, and the differences were statistically significant (P<0.05). The level of C-reactive protein in Wagner 2-3 group was higher than that in Wagner 1 group, and HCT and ALB were lower than those in Wagner 1 group, the differences were statistically significant (P<0.05). Wagner grade of type 2 diabetes mellitus complicated with diabetic foot was negatively correlated with serum HCT and ALB levels (rs<0, P<0.05), but not with |HCT-ALB| (P>0.05). Conclusion Serum HCT and ALB levels are closely related to Wagner grade of patients with type 2 diabetes mellitus complicated with diabetic foot, which can provide a reference for evaluating the severity of the disease to a certain extent.
尚俊良 王广宇 石春红 徐旭英. 2型糖尿病并发糖尿病足患者Wanger分级与红细胞压积、白蛋白、红细胞压积和白蛋白差值的相关性[J]. 中国医药导报, 2023, 20(21): 72-75.
SHANG Junliang WANG Guangyu SHI Chunhong XU Xuying. Correlation of Wanger grade with hematocrit, albumin, difference of hematocrit and albumin in patients with type 2 diabetes mellitus complicated with diabetic foot. 中国医药导报, 2023, 20(21): 72-75.