Study on medication rules of Professor Chen Bainan in treating chronic venous insufficiency of lower limbs based on data mining
ZHANG Xiaoqian1 FAN Qichen2 WANG Genyi2 WANG Yannan3
1.College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Shandong Province, Jinan 250014, China;
2.the First Clinical College, Shandong University of Traditional Chinese Medicine, Shandong Province, Jinan 250014, China;
3.Department of Peripheral Vascular Diseases, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Shandong Province, Jinan 250014, China
Abstract：Objective To summarize the medication rules of Professor Chen Bainan in treating chronic venous insufficiency (CVI) of lower limbs. Methods The clinical prescriptions of Professor Chen Bainan for the treatment of CVI in the Outpatient Department of Peripheral Vascular Disease, Affiliated Hospital of Shandong University of Traditional Chinese Medicine from January 2017 to March 2022 were collected. The methods of frequency analysis, association rule analysis, topological data analysis, and cluster analysis were used to analyze drug frequency, nature and flavour, channel tropism, new prescription construction, and drug combination, and to explore the rule of drug use. Results A total of 520 prescriptions were collected in this study, including 152 traditional Chinese medicine, among which 35 were high-frequency traditional Chinese medicine. High-frequency drugs were clearing heat drugs, promoting blood circulation for removing blood stasis drugs, tonifying drugs. The drug natures were mostly cold or warm, the drug flavours were bitter, pungent or sweet, the drugs main into the liver channel. A total of 24 strong association rules were obtained, one new formula was constructed, and and three cluster combinations were obtained. Conclusion Professor Chen Baonan’s medication rules for CVI treatment is to promote blood and detoxification, taking into account strengthening vital qi, advocating the regulation of qi movement, regulating qi and activating blood, paying attention to dampness pathogen, and being good at removing dampness flexibly.
张筱茜1 范琦琛2 王艮一2 王雁南3. 基于数据挖掘研究陈柏楠教授治疗下肢慢性静脉功能不全的用药规律[J]. 中国医药导报, 2023, 20(21): 29-34.
ZHANG Xiaoqian1 FAN Qichen2 WANG Genyi2 WANG Yannan3. Study on medication rules of Professor Chen Bainan in treating chronic venous insufficiency of lower limbs based on data mining. 中国医药导报, 2023, 20(21): 29-34.
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