Abstract：Objective To investigate the image features combined with pathological changes of inflammatory myofiroblastic tumor (IMT), in order to improve diagnostic level. Methods From May 2008 to December 2017, in Fujian Province Tumor Hospital, the CT and MRI findings of 11 patients with IMT confirmed by histopathology on surgically resected specimen were retrospectively. The location, size, shape, density or signal, and contrast enhancement of these tumors were analyzed. Results In 11 cases of IMT, 3 cases occurred in lung, 2 cases oceurred in stomach, abdominal cavity, abdominal wall, mesentery, bladder, ureter and leg soft tissue was 1 case respectively. Tumor characterized by solid soft tissue mass 7 cases, 4 cases of cystic or solid mass. The density or signal of the most tumor was uneven, and 1 case lesion could be seen calcification. The majority of cases had a clear boundary. After contrast administration, moderate or marked homogeneous or heterogeneous enhancement, it was found. IMT occurred in abdominal cavity, abdominal wall and mesentery had invasive imaging features. The tumors were mainly composed of spindle shaped fibrous cells and inflammatory cells on pathology, and positive staining for muscle deriving proteins was observed immunohistochemically. The wave type protein (Vimentin) was positive in 10 patients, the smooth muscle actin (SMA) was positive in 8 patients, the muscle actin (MSA) was positive in 5 patients, and ALK, S-100 protein, CD117 and CD34 were all negative. Conclusion IMT is a rane tumor, and its imaging features hawe certain value for localization and qualitation diagnosis, but the diagnosis stiu needs to rely on pathological examination.
[1] Fetcher CD，Until KK，Merterm F. World Health Organization classffication of tumours pathology And genetics of tomours of soft tissue and bone [M]. Lyon：IARC Press，2002：47-107.
[2] 林达，相世峰，冯国飞，等.肝脏炎性肌纤维母细胞瘤的CT、MRI表现及病理特征[J].中华肝胆外科杂志，2017， 23（9）：591-596.
[3] Liu B，Xu J，Wang J，et al. Computed tomography appearance of inflammatory myofibroblastic tumor in the abdomen：CT features and pathologic correlation [J]. Int J Exp Med，2015，8（9）：16745-16755.
[4] Magill JC，Ferguson MS，Butler CＲ，et al. Inflammatory myofibroblastic tumor of the tonsil：case report and literature review [J]. J Laryngol Otol，2010，124（10）：1123-1125.
[5] Gallego L，Santamarta TＲ，Blanco V，et al. Inflammatory myofibroblastic tumor of the lung and the maxillary region：a benign lesion with aggressive behavior [J]. Case Rep Dent，2013，2013：879 792.
[6] 李蒙，吴宁，林冬梅，等.炎性肌纤维母细胞瘤的多层螺旋CT表现[J].中国医学影像技术，2008，24（12）：1995-1998.
[7] 毛荣军，李启明，樊长姝，等.腹腔脏器炎性肌纤维母细胞瘤及其相关病变的临床病理、免疫组化及超微结构研究[J].实用癌症杂志，2008，23（3）：233，239.
[8] 赵曦瞳，岳松伟，程强，等.不同病理分型炎性肌纤维母细胞瘤CT表现分析[J].中华医学杂志，2017，97（1）：43-46.
[9] 陈天忠，李涛，龙光宇，等.肝脏炎性肌纤维母细胞瘤的CT、MRI表现及其与病理对照分析[J].实用放射学杂志，2016，32（11）：1706-1709.
[10] 王春，杨秀荣，马周鹏，等.腹膜后炎性肌纤维母细胞瘤的CT特征[J].中华放射学杂志，2016，50（12）：954-596.
[11] 史瑞雪，王丽，余梦菊，等.肺外炎性肌纤维母细胞瘤的影像学表现与病理对照[J].中国CT和MRI杂志，2014， 12：50-52.
[12] 侯刚，夏钰弘.胃肠道炎性肌纤维母细胞瘤的CT与病理关系分析[J].中国临床医学影像杂志，2014，25（1）：48-50.
[13] 陶磊，崔文静，卢光明.肺炎性肌纤维母细胞瘤的CT影像表现及病理对照[J].临床放射学杂志，2017，36（10）：1531-1534.
[14] 张秀芸.肺部炎性肌纤维母细胞瘤16例患者的CT表现及病理分析[J].中国CT和MRI杂志，2017，15（9）：67-69.
[15] 许奇俊，邢振，游瑞雄，等.腹盆腔内炎性肌纤维母细胞瘤CT/MRI表现（附8例报告并文献复习）[J].临床放射学杂志，2016，35（4）：565-569.
[16] 刘伯胜，刘赤岩，陶福典.肠系膜及腹膜后炎性肌纤维母细胞瘤的CT表现初探[J].临床放射学杂志，2016，35（10）：1616-1617.
[17] 孙海涛，刘锴，王艳秋，等.腹部炎性肌纤维母细胞瘤以病理为基础的影像学特征[J].放射学实践，2017，32（2）：162-166.
[18] 钱斌，吴晶涛，胡晓华，等.泌尿系统炎性肌纤维母细胞瘤的CT影像学特征分析[J].中华泌尿外科杂志，2013， 34（3）：204-207.
[19] 田向永，宋金桐，邢会武，等.膀胱炎性肌纤维母细胞瘤六例报告并文献复习[J].中华泌尿外科杂志，2017，38（3）：178-181.
[20] 任转琴，陈涛，张雷，等.软组织炎性肌纤维母细胞瘤的CT、MRI诊断[J].中国医学影像学杂志，2009，17（6）：462-464.
2018, Vol. 15 
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