Effect of compound polyethylene glycol electrolyte combined with Lin-alotide on bowel preparation before colonoscopy in patients with functional constipation
WU Zhenxing LIN Ying
Department of Gastroenterology, Taizhou First People’s Hospital, Zhejiang Province, Taizhou 318020, China
Abstract：Objective To analyze the effect of combined application of compound polyethylene glycol electrolyte and Linalotide on bowel preparation before colonoscopy in patients with functional constipation. Methods A total of 155 patients with functional constipation underwent colonoscopy in Taizhou First People’s Hospital of Zhejiang Province from October 2020 to October 2021 were selected and divided into control group (77 cases) and study group (78 cases) according to random number table method. The control group used compound polyethylene glycol electrolyte for intestinal preparation. The study group used compound polyethylene glycol electrolyte combined with Linalotide for intestinal preparation. Gastrointestinal symptom grading scale scores, bowel sound time, and anal exhaust time of the two groups were compared two days before examination and one day after examination, and intestinal cleanliness, subjective tolerance, and adverse reactions of the two groups were recorded. Results After one day of examination, the scores of gastrointestinal symptom rating scale in both groups were lower than those at two days before examination, and those in the study group were lower than those in the control group (P＜0.05). After one day of examination, the bowel sound time and anal exhaust time of the two groups were shorter than those at two days before examination, and those in the study group were shorter than those in the control group (P＜0.05). The subjective tolerance and intestinal cleanliness of the study group were better than those of the control group (P＜0.05). There was no significant difference in the total incidence of adverse reactions between the two groups (P＞0.05). Conclusion The combination of compound polyethylene glycol electrolyte and Linalotide for intestinal preparation before colonoscopy effectively improve the peristaltic function of the patients, and significantly increase the intestinal cleaning ability, achieve the effect of improving the degree of subjective tolerance of patients.
吴振兴 林颖. 复方聚乙二醇电解质联合利那洛肽在功能性便秘患者肠镜检查前肠道准备中的应用效果[J]. 中国医药导报, 2023, 20(19): 108-111.
WU Zhenxing LIN Ying. Effect of compound polyethylene glycol electrolyte combined with Lin-alotide on bowel preparation before colonoscopy in patients with functional constipation. 中国医药导报, 2023, 20(19): 108-111.
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