Progress in the application of zebra fish model in cancer research
WU Zhibin1 ZHANG Huanghui1 LI Rongxing1 SUN Nongyuan1 LIU Zhaoxia1 HE Fan2 YANG Bing2
1.The First Clinical College of Medicine, Guizhou University of Traditional Chinese Medicine, Guizhou Province, Guiyang 550002, China;
2.Department of Oncology, the First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guizhou Province, Guiyang 550001, China
Abstract：Searching for a reasonable and effective tumor model is crucial for tumor research. In recent years, zebra fish has been favored by researchers because of its high genetic similarity with human, transparent embryos and larvae, strong reproductive ability, short research period, and low cost, and has been used in the research of various tumor models such as colorectal cancer, liver cancer, and cervical cancer. This paper summarizes the recently published zebra fish tumor models, clarifies their construction methods, digs deep into their application value, explains their pros and cons, and briefly discusses on the prospects of zebra fish in tumor prevention and treatment, fundamentally expects to provide a reference for the application of zebra fish tumor models.
吴志斌1 张煌辉1 李荣幸1 孙农苑1 刘朝霞1 贺凡2 杨兵2. 斑马鱼模型在肿瘤研究中的应用进展[J]. 中国医药导报, 2023, 20(15): 45-48,60.
WU Zhibin1 ZHANG Huanghui1 LI Rongxing1 SUN Nongyuan1 LIU Zhaoxia1 HE Fan2 YANG Bing2. Progress in the application of zebra fish model in cancer research. 中国医药导报, 2023, 20(15): 45-48,60.
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