Abstract：Objective To investigate the clinical effects of self-made Qingyu Hejiang Decoction Tang in treating patients with liver and stomach stagnation-heat type of reflux esophagitis (RE). Methods Ninety-eight cases of RE patients admitted to Zigong First People’s Hospital, Sichuan Province from January 2021 to April 2022 were selected and divided into control and observation groups using the random number table method, with 49 cases in each group. The control group was treated with conventional western medicine, while the observation group was treated with the addition of self-made Qing Yu and Hejiang Decoction. Both groups were treated with 14 d as a course of treatment, and a total of three courses of treatment were given. The efficacy of the two groups was compared, the traditional Chinese medicine symptom score and esophageal kinetics before and after treatment in both groups, and the occurrence of adverse reactions was recorded. Results After the treatment, the points of acid reflux and heartburn, abdominal distension and fullness, belching and early satiety, loss of appetite, and red tongue with yellow coating in both groups were lower than those before treatment, while those in the observation group were lower than those in the control group， and the differences were statistically significant (P＜0.05). After treatment, the esophageal sphincter pressure, lower esophageal sphincter pressure, and distal esophageal contraction points in both groups were higher than before treatment, while those in the observation group were higher than those in the control group, and the differences were statistically significant (P＜0.05). The clinical efficacy of the observation group was better than that of the control group, and the difference was statistically significant (P＜0.05). The difference was not statistically significant when comparing the total incidence rate during treatment between the two groups (P＞0.05). Conclusion The self-made Qingyu Hejiang Decoction is effective in treating RE with liver and stomach stagnation and heat, and can effectively improve clinical symptoms and esophageal dynamics with high safety.
刘洁 朱琦 陈新 白少玉 任登杰. 自拟清郁和降汤治疗肝胃郁热型反流性食管炎患者的临床效果[J]. 中国医药导报, 2023, 20(13): 100-103.
LIU Jie ZHU Qi CHEN Xin BAI Shaoyu REN Dengjie. Clinical effects of self-made Qingyu Hejiang Decoction in treating patients with liver and stomach stagnation-heat type of reflux esophagitis. 中国医药导报, 2023, 20(13): 100-103.
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