Study on traditional Chinese medicine syndrome characteristics and traditional Chinese medicine medication law of primary Sjogren’s syndrome based on data mining
WEI Naxin SUN Hongyan
College of Traditional Chinese Medicine, Xinjiang Medical University Institute of Traditiaonal Chinese Medicine, Xinjiang Uygur Autonomous Region, Urumqi 830017, China
Abstract：Objective To excavate and analyze the literature on the treatment of primary Sjogren’s syndrome (pSS) by traditional Chinese medicine, and to summarize the syndrome characteristics and medication rules of pSS. Methods The literature related to traditional Chinese medicine treatment of pSS from January 2011 to December 2021 was retrieved from CNKI and Wanfang data, and the traditional Chinese medicine syndrome elements, tongue and pulse, prescriptions, and so on were counted successively by Excel. SPSS 25.0, SPSS Modeler and Cytoscape were used for cluster analysis, association analysis, and complex network analysis respectively. Results A total of 145 literatures were included, and the syndrome types were mainly Qi and Yin deficiency. The tongue pulse was mainly fine pulse, red tongue, number pulse, and moss stripping. In addition to the self-designed formula, Yiwei decoction was often used; there were 197 kinds of traditional Chinese medicines involved, mainly ophiopogon ophiopogon, licorice and radix rehmanniae. The medicinal tastes were mainly sweet, bitter and pungent, while the medicinal properties were mainly cold and flat, which were mainly attributed to the three classics of lung, liver, and stomach. Seven core drug groups were obtained by systematic cluster analysis. A total of 14 groups of association rules were obtained by association analysis. Complex network analysis showed that the core drug combinations were ophiopogon ophiopogon, Radix rehmanniae, Radix ginseng and licorice. Conclusion pSS syndrome type is based on “Qi and Yin deficiency, stasis, toxicity, phlegm, and dampness as the standard”, and the treatment is based on “tonifying liver and kidney, tonifying lung and tonifying stomach”, supplemented by activating blood circulation and removing blood stasis, clearing heat and cooling blood, regulating qi, and so on.
位娜鑫 孙红艳. 基于数据挖掘研究原发性干燥综合征的中医证候特点及中医用药规律[J]. 中国医药导报, 2023, 20(11): 9-13.
WEI Naxin SUN Hongyan. Study on traditional Chinese medicine syndrome characteristics and traditional Chinese medicine medication law of primary Sjogren’s syndrome based on data mining. 中国医药导报, 2023, 20(11): 9-13.
京公网安备 11010502046598号