Abstract：Objective To investigate the clinical effect of Cheqian Lingzhu Decoction, an experienced prescription of Professor Cheng Jiazheng, a famous old Chinese medicine in Shanghai, on children with diarrhea of damp heat type. Methods A total of 160 children with diarrhea of damp heat admitted to Shuguang Hospital, Shanghai University of Traditional Chinese Medicine from May 2021 to January 2022, they were divided into test group and control group, with 80 cases in each group. On the premise of basic treatment, the test group was given Cheqian Lingzhu Decoction Granules orally; the control group was given a shaped placebo of Cheqian Lingzhu Decoction on the premise of basic treatment. The total score of main symptoms, total score of concomitant symptoms, quality of life assessment, clinical efficiency, and safety were evaluated. Results After treatment, the main symptom score, concomitant symptom score, and total symptom score were decreased in both groups, and the treatment group was lower than the control group, the differences were statistically significant (P＜0.05). After treatment, the quality of life scores of the two groups were lower than those before treatment, the differences were statistically significant (P＜0.05), but there was no statistically significant difference between the two groups (P＞0.05). The syndrome efficacy and disease efficacy of experimental group were better than those of control group, and the differences were statistically significant (P＜0.05). There were no adverse reactions in the two groups. Conclusion Cheqian Lingzhu Decoction can obviously improve the symptoms and signs of children with damp heat diarrhea, improve the clinical effect, and help to quickly relieve the discomfort symptoms of children with diarrhea of damp heat type.
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