Effects of different delivery mode on neonatal infection in pregnant women with group B streptococcus and analysis of related influencing factors
ZHANG Tongqing WANG Ming ZHAO Xuanyu JIANG Haili#br#
Department of Maternal and Fetal Medicine, Beijing Obstetrics and Gynecology Hospital, Capital Medical University Beijing Maternal and Child Health Care Hospital, Beijing 100026, China
Abstract：Objective To explore the effects of different delivery mode on neonatal infection in pregnant women with group B streptococcus (GBS) and to analyzed of related influencing factors. Methods Retrospective study was conducted on the clinical data of 1 376 pregnant women with GBS bacteria during pregnancy and delivery in Beijing Obstetrics and Gynecology Hospital, Capital Medical University from January 2017 to December 2018. According to different delivery methods, they were divided into vaginal delivery group and cesarean section group, and according to the infection of newborns, they were divided into GBS positive group and GBS negative group. GBS infection and its influencing factors in neonates under different delivery mode were analyzed. Results There were 999 pregnant women and 999 newborns delivered vaginally; there were 377 pregnant women and 388 newborns during cesarean section. There were 79 positive cases of GBS in vaginal delivery group and 12 positive cases in cesarean section group; there was statistical significance in neonatal infection between two groups (P＜0.05). There were no significant differences in age, gestational age at delivery, proportion of premature rupture of membranes between two groups (P＞0.05); there was statistical significance in the proportion of antibiotic treatment between two groups (P＜0.05). Forceps assisted labor and natural delivery, the use of Penicillin and Cefazolin was influencing factors for neonatal GBS infection (P＜0.05). Conclusion Different delivery modes of pregnant women with GBS in the third trimester of pregnancy are related to neonatal GBS infection, and application of antibiotics can reduce the incidence of neonatal GBS infection.
张同庆 王明 赵轩宇 姜海利. B族溶血性链球菌带菌孕妇不同分娩方式对新生儿感染的影响及相关影响因素分析[J]. 中国医药导报, 2023, 20(6): 104-107.
ZHANG Tongqing WANG Ming ZHAO Xuanyu JIANG Haili. Effects of different delivery mode on neonatal infection in pregnant women with group B streptococcus and analysis of related influencing factors. 中国医药导报, 2023, 20(6): 104-107.
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