针灸结合经皮椎体后凸成形术治疗骨质疏松性椎体压缩性骨折的meta分析

doi:10.20047/j.issn1673-7210.2023.06.20

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摘要目的系统评价针灸结合经皮椎体后凸成形术（PKP）治疗骨质疏松性椎体压缩性骨折（OVCF）的效果。方法检索收录于中国生物医学文献数据库、万方数据库、中国知网、维普网、Cochrane Library、Embase、PubMed中关于针灸结合PKP治疗OVCF的随机对照试验文献。检索时限为建库至2022年4月。使用RevMan 5.3软件系统进行meta分析。结果最终纳入9篇文献，共包含626例研究对象。meta分析结果显示，试验组总有效率高于对照组（OR=4.80，95%CI：2.15～10.75，P=0.000 1）；试验组治疗后1个月视觉模拟评分法（VAS）评分（SMD=-1.65， 95%CI：-1.95～-1.35，P＜0.000 01）及治疗后6个月VAS评分（SMD=-1.22，95%CI：-1.54～-0.89，P＜0.000 01）均低于对照组；试验组功能障碍指数评分低于对照组（SMD=-1.51，95%CI：-1.74～-1.29，P＜0.000 01）；两组治疗后1个月的Cobb角（SMD=-0.09，95%CI：-0.38～0.21，P=0.57）及两组治疗后6个月的Cobb角（SMD=-0.06，95%CI：-0.36～0.24，P=0.39）比较，差异无统计学意义。结论针灸结合PKP治疗OVCF的效果优于单纯PKP，值得临床推广应用。

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	潘成镇1 林宗汉2 邬尚忠2 商志浩1 韦沅汛1 韦宗波1 杨靖芸1 覃琳瑜1

关键词 ：针灸, 经皮椎体后凸成形术, 骨质疏松性椎体压缩性骨折, meta分析

Abstract：Objective To systematically evaluate the effect of acupuncture and moxibustion combined with percutaneous kyphoplasty (PKP) in the treatment of osteoporotic vertebral compression fracture (OVCF). Methods Randomized controlled trial literatures on acupuncture and moxibustion combined with PKP in the treatment of OVCF were searched from China Biology Medicine disc, Wanfang Data, CNKI, VIP, Cochrane Library, Embase, and PubMed. The search period was from the inception to April 2022. Meta-analysis was performed by RevMan 5.3 software system. Results Finally, nine literatures were included, including a total of 626 subjects. Meta-analysis showed that the total effective rate of the experimental group was higher than that of the control group (OR=4.80, 95%CI: 2.15 to 10.75, P=0.000 1). Visual analog scale (VAS) scores of the experimental group at one month after treatment (SMD=-1.65, 95%CI: -1.95 to -1.35, P＜0.000 01) and VAS scores at six months after treatment (SMD=-1.22, 95%CI: -1.54 to -0.89, P＜0.000 01) were lower than those of the control group. The Oswestry disability index of the experimental group was lower than that of the control group (SMD=-1.51, 95%CI: -1.74 to -1.29, P＜0.000 01). There were no significant differences in Cobb angle at one month after treatment (SMD=-0.09, 95%CI: -0.38 to 0.21, P=0.57) and the Cobb angle at six months after treatment (SMD=-0.06, 95%CI: -0.36 to 0.24, P=0.39) between the two groups. Conclusion Acupuncture and moxibustion combined with PKP treatment OVCF is better than PKP alone, and is worthy of clinical promotion and application.

Key words： Acupuncture and moxibustion Percutaneous kyphoplasty Osteoporotic vertebral compression fracture Meta-analysis

基金资助:广西壮族自治区卫生健康委员会自筹经费科研课题（Z20190578）；
广西壮族自治区崇左市科技计划项目（崇科FC2019005）；
广西中医药大学自然科学研究项目（2019M S030）。

通讯作者: 邬尚忠（1984-），男，硕士；研究方向：脊柱退变性疾病的基础和临床微创治疗。

作者简介: 潘成镇（1998-），男，广西中医药大学研究生院2021级中医骨伤科学专业在读硕士研究生；研究方向：脊柱、四肢骨关节创伤性疾病的中医药防治。

引用本文:

潘成镇1 林宗汉2 邬尚忠2 商志浩1 韦沅汛1 韦宗波1 杨靖芸1 覃琳瑜1. 针灸结合经皮椎体后凸成形术治疗骨质疏松性椎体压缩性骨折的meta分析[J]. 中国医药导报, 2023, 20(6): 90-94.
PAN Chengzhen1 LIN Zonghan2 WU Shangzhong2 SHANG Zhihao1 WEI Yuanxun1 WEI Zongbo1 YANG Jingyun1 QIN Linyu1. Meta-analysis of acupuncture and moxibustion combined with percutaneous kyphoscoplasty in the treatment of osteoporotic vertebral compression fracture. 中国医药导报, 2023, 20(6): 90-94.

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