Research progress of autophagy and liver fibrosis and regulation of traditional Chinese medicine
PENG Yunhe LI Yuan ZHANG Kan HUANG Guye
Department of Hepatic Diseases, the First Affiliated Hospital of Guangxi University of Chinese Medicine, Guangxi Zhuang Autonomous Region, Nanning 530023, China
Abstract：Autophagy is closely related to the development of liver fibrosis. It plays an important role in the hepatic stellate cells activation and affects the development of liver fibrosis through autophagy related proteins and signaling pathways. Many non-coding RNA regulate autophagy exert biological effects in liver fibrosis and may become a new treatment strategy for liver fibrosis. Traditional Chinese medicine can play an anti fibrosis role through the autophagy and regulate autophagy in a dual manner. This paper discusses the traditional Chinese medicine research of autophagy regulation in liver fibrosis, and discusses the shortcomings of the current research, in order to provide a theoretical basis for the further research of autophagy in the prevention and treatment of liver fibrosis with traditional Chinese medicine.
彭云鹤 李媛 张衎 黄古叶. 自噬与肝纤维化及中医药调控的研究进展[J]. 中国医药导报, 2023, 20(4): 52-55,63.
PENG Yunhe LI Yuan ZHANG Kan HUANG Guye. Research progress of autophagy and liver fibrosis and regulation of traditional Chinese medicine. 中国医药导报, 2023, 20(4): 52-55,63.
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