Study on medication rules of skin-type henoch-schonlein purpura in Chinese Medical Code based on data mining
CUI Zhengjiu1 ZHOU Xu2 WANG Xinxin3 MA Yunhong4 WANG Shuangyi1 DIAO Juanjuan2 PAN Yueli2
1.The First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Shandong Province, Jinan 250014, China;
2.Department of Pediatrics, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Shandong Province, Jinan 250013, China; 3.Department of Pediatrics, Rizhao Hospital of Traditional Chinese Medicine, Shandong Province, Rizhao 276800, China;
4.College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Shandong Province, Jinan 250014, China
Abstract：Objective To explore the medication characteristics and prescription rules of skin-type henoch-schonlein purpura prescription in Chinese Medical Code. Methods The prescriptions for the treatment of skin-type henoch-schonlein purpura in the whole database of the Chinese Medical Code were retrieved, and the drug database was screened and established. The Traditional Chinese Medicine Inheritance Computing Platform V3.0 was used for data mining, and drug frequency, nature and flavour, channel tropism, efficacy, and high-frequency drug combination were analyzed, and association rules and cluster analysis were carried out. Results A total of 232 prescriptions for the treatment of skin-type henoch-schonlein purpura were obtained, including 228 traditional Chinese medicines, 34 herbs were used with a frequency of≥20 times. Most of the drugs used were cold, warm, and plain nature; bitter, sweet, and pungent flavours. They mainly belonged to the lung, stomach, spleen, heart, and liver channels. Most of the effects were clearing heat, tonifying deficiency, relieving surface, resolving phlegm, relieving cough and asthma, regulating qi-flowing classes. Through analysis,17 high-frequency drug combinations, four association rules between drugs and three types of new prescriptions were obtained. Conclusion With clearing the defensive qi, nutrient-blood, and heat pathogen as the core, supplemented by promoting blood circulation, drying dampness, invigorating qi to relieve surface, regulating qi and eliminating phlegm and other treatment methods is the prescription medication rules of Chinese Medical Code for the treatment of skin-type henoch-schonlein purpura.
崔正九1 周旭2 王欣欣3 马云虹4 王双翼1 刁娟娟2 潘月丽2. 基于数据挖掘的《中华医典》中皮肤型过敏性紫癜用药规律研究[J]. 中国医药导报, 2023, 20(3): 113-117.
CUI Zhengjiu1 ZHOU Xu2 WANG Xinxin3 MA Yunhong4 WANG Shuangyi1 DIAO Juanjuan2 PAN Yueli2. Study on medication rules of skin-type henoch-schonlein purpura in Chinese Medical Code based on data mining. 中国医药导报, 2023, 20(3): 113-117.
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