Comparative study of Guangchenpi and Chenpi under the influence of planting environment on secondary metabolites
SHI Hongchao1 SHANG Xueying1 CHEN Mingquan1 LUO Zhuoya2 QIN Ren’an1 HE Fenglei1 SUN Dong1
1.Guangzhou Baiyunshan Pharmaceutical Co. Chenliji, Guangdong Province, Guangzhou 510288, China;
2.Guangdong Institute For Drug Control, Guangdong Province, Guangzhou 510663, China
Abstract:Objective To compare the effects of planting environment on secondary metabolites between Guangchenpi and Chenpi. Methods Liquid chromatography-mass spectrometry was used to analyze and identify the differential components in Chenpi samples from different varieties. The peak area ratio of the differential flavonoid components between Guangchenpi and Chenpi at 283 nm, the peak area ratio of the differential components in Chenpi from different regions was analyzed. Results There were six differential components Chenpi samples from different regions, including hesperidin, sinensetin, 6-demethoxyhesperetin, nobiletin, hesperetin, and 5-demethylnobiletin. The ratio sinensetin/6-demethoxy- hesperidin>0.60 or hesperidin/5-demethoxyhesperidin>7.00 was Guangchenpi, and the ratio sinensetin/6-deme-thoxyhesperidin≤0.60 or hesperidin/5-demethoxyhesperidin≤7.00 was Chenpi. Conclusion In this study, the peak area ratio of sinensetin/6-demethoxyhesperidin>0.60 or hesperidin/5-demethylnobiletin>7.00 at 283 nm wavelength is used as the basis for the determination of Guangchenpi, which can improve the convenience and universality of the classification index of Chenpi origin.
石洪超1 商雪莹1 陈明权1 罗卓雅2 覃仁安1 何风雷1 孙东1. 基于种植环境对次生代谢产物影响下的广陈皮与陈皮对比研究[J]. 中国医药导报, 2023, 20(3): 104-108,117.
SHI Hongchao1 SHANG Xueying1 CHEN Mingquan1 LUO Zhuoya2 QIN Ren’an1 HE Fenglei1 SUN Dong1. Comparative study of Guangchenpi and Chenpi under the influence of planting environment on secondary metabolites. 中国医药导报, 2023, 20(3): 104-108,117.