Application of mesoporous silica nanoparticles in drug delivery
OUYANG Xianjin KANG Xu GUO Tingting LIU Yueping CHANG Mingming
College of Bioscience and Resources Environment, Beijing University of Agriculture, Key Laboratory of Urban Agriculture in North China, Ministry of Agriculture and Rural Affairs,Beijing 102206, China
Abstract:Mesoporous silica nanoparticles with ordered mesoporous structure, large specific surface area, easy surface modification, and high colloidal stability have attracted more and more attention in the field of drug targeted therapy and controlled-release. As a drug carrier, unmodified mesoporous silica has a relatively obvious “sudden release” effect, by modifying small organic molecules, inorganic nanoparticles, and ring molecules on its surface, the drug release efficiency can be effectively improved, which is beneficial to improve the stability and biocompatibility of the system, and promote the further application of mesoporous silica nanoparticles in the field of drug delivery.
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