Study on the improvement of quality standard for scutellriae Radix Scutellariae
SUN Qiannan ZHANG Jianping QU Xiaoyan TA Na GAO Han GUO Baofeng
Chinese and Mongolian Medicine Standard Research Laboratory, Inner Mongolia Institute for Drug Control, Inner Mongolia Autonomous Region, Huhehot 010020, China
Abstract：Objective To improve the quality standard of the scutellriae Radix Scutellariae. Methods Six batches of scutellaria Radix Scutellariae samples were qualitatively identified by microscopy and thin-layer chromatography. The contents of moisture, total ash, acid insoluble ash and extract of six batches of samples were determined by referring to the general rules of Pharmacopoeia of the People’s Republic of China (2020 Edition). The quantitative analysis of baicalin and han baicalin in six batches of samples was carried out by high performance liquid chromatography. Results The average values of moisture, total ash, acid insoluble ash and extract were 9.8%, 8.0%, 3.2% and 48.5%, respectively. Baicalin had a good linear relationship with peak area in the range of 84.119 2-841.192 8 ng (r = 0.999 9), the recovery was 101.51%, RSD were 1.60%. Han baicalin had a good linear relationship with peak area in the range of 38.769 6-387.6960 ng, there was a good linear relationship with the peak area (r = 1.000 0). The recovery rate was 102.83%, RSD were 2.00%. The contents of baicalin and han baicalin in six batches of samples were 6.99%-10.19 % and 2.30%-2.72%, respectively. Conclusion The quality control method of scutellriae Radix Scutellariae is improved by qualitative and quantitative methods.
孙倩男 张建平 渠晓艳 塔娜 高寒 郭宝凤. 粘毛黄芩质量标准提高研究[J]. 中国医药导报, 2023, 20(3): 24-28.
SUN Qiannan ZHANG Jianping QU Xiaoyan TA Na GAO Han GUO Baofeng. Study on the improvement of quality standard for scutellriae Radix Scutellariae. 中国医药导报, 2023, 20(3): 24-28.
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