Visual analysis of traditional Chinese and western medicine treatment of infantile spasms based on VOSviewer and CiteSpace
AN Zimeng FU Qianfang CHEN Zhaoyuan WANG Heyu ZHANG Xilian▲
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China
Abstract：Objective To analyze the current situation and development trend of Chinese and western medicine in the treatment of infantile spasms (IS) in the past 50 years. Methods Relevant literature from January 1975 to June 2022 in CNKI, Wanfang, VIP, and CBM were searched. VOSviewer and CiteSpace were used to draw the author’s cooperation density map, keyword co-occurrence, cluster analysis map, etc., and conduct visual analysis of the author and keyword information. Results A total of 1 767 papers were included, and the number of papers published in this field showed a gradual upward trend. The author with the highest amount of western medicine publications was Zou Liping; Chinese medicine was Liu Jinmin. Western medicine with the largest number of papers was adrenocorticotropic hormone, and the traditional Chinese medicine was Chaibei Zhixian Decoction. Eight cluster labels were formed through visualization software, and the cluster with the highest number of nodes was cerebral palsy. The research was carried out according to the etiology, treatment methods, and Chinese and western medicine, etc. The development trend was analyzed according to the treatment concepts and methods. Conclusion Integrative traditional Chinese and western medicine has a good prospect in treating IS, and precise treatment and the ketogenic diet may become hot spots in the future.
安子萌 付乾芳 陈朝远 王贺昱 张喜莲▲. 基于VOSviewer与CiteSpace的中西医治疗婴儿痉挛症的可视化分析[J]. 中国医药导报, 2022, 19(36): 96-100.
AN Zimeng FU Qianfang CHEN Zhaoyuan WANG Heyu ZHANG Xilian▲. Visual analysis of traditional Chinese and western medicine treatment of infantile spasms based on VOSviewer and CiteSpace. 中国医药导报, 2022, 19(36): 96-100.
[1] Specchio N，Wirrell EC，Scheffer IE，et al. International League Against Epilepsy classification and definition of epilepsy syndromes with onset in childhood：Position paper by the ILAE Task Force on Nosology and Definitions [J]. Epilepsia，2022，63（6）：1398-1442.
[2] Mytinger JR. Definitions and Diagnostic Criteria for Infantile Spasms and West Syndrome-Historical Perspectives and Practical Considerations [J]. Semin Pediatr Neurol，2021， 38：100893.
[3] Riikonen R. Epidemiological data of West syndrome in Finland [J]. Brain Dev，2001，23（7）：539-541.
[4] Howell KB，Freeman JL，Mackay MT，et al. The severe epilepsy syndromes of infancy：A population-based study [J]. Epilepsia，2021，62（2）：358-370.
[5] O’Callaghan FJ，Edwards SW，Alber FD，et al. Safety and effectiveness of hormonal treatment versus hormonal treatment with vigabatrin for infantile spasms （ICISS）：a randomised，multicentre，open-label trial [J]. Lancet Neurol，2017，16（1）：33-42.
[6] Baba S，Okanishi T，Homma Y，et al. Efficacy of long-term adrenocorticotropic hormone therapy for West syndrome：A retrospective multicenter case series [J]. Epilepsia Open，2021，6（2）：402-412.
[7] 张端秀，廖建湘，万力生.婴儿痉挛症中西医治疗研究进展[J].中国中西医结合儿科学，2011，3（3）：232-235.
[8] 马融，韩新民.全国高等院校中医药类专业卫生部“十二五”规划教材·中医儿科学[M].北京：人民卫生出版社，2012.
[9] 丁学东.文献计量学基础[M].北京：北京大学出版社，1992.
[10] Osborne JP，Lux AL，Edwards SW，et al. The underlying etiology of infantile spasms（West syndrome）：information from the United Kingdom Infantile Spasms Study（UKISS）on contemporary causes and their classification [J]. Epilepsia，2010，51（10）：2168-2174.
[11] Wang QH，Cao JJ，Wang YY，et al. Efficacy of levetiracetam in STXBP1 encephalopathy with different phenotypic and genetic spectra [J]. Seizure，2022，95：64-74.
[12] Krey I，Krois-Neudenberger J，Hentschel J，et al. Genotype-phenotype correlation on 45 individuals with West syndrome [J]. Eur J Paediatr Neurol，2020，25：134-138.
[13] Lux AL. Latest American and European updates on infantile spasms [J]. Curr Neurol Neurosci Rep，2013，13（3）：334.
[14] Zhang J，Chen G，Wang J，et al. Efficacy of the ketogenic diet on ACTH- or corticosteroid-resistant infantile spasm：a multicentre prospective control study [J]. Epileptic Disord，2021，23（2）：337-345.
[15] 张青，杨洞洞，丁成赟，等.中医体质与癫痫难治性相关性探讨[J].广州中医药大学学报，2022，39（1）：7-11.
[16] 王星辰，马融.马融从“少火生气”论治婴儿痉挛症经验[J].中华中医药杂志，2021，36（12）：7141-7144.
[17] 孙江燕，王潇慧，刘冲冲，等.柴贝止痫汤联合抗痫药物治疗痰气郁滞证耐药性癫痫伴意识障碍的局灶发作患者34例随机对照试验[J].中医杂志，2021，62（9）：796- 801.
[18] 董笑克.柴贝止痫汤抗痫作用机制及其物质基础研究[D].北京：北京中医药大学，2021.
[19] 张青，杨洞洞，王潇慧，等.柴贝止痫汤对KA致痫大鼠行为学及N-cadherin、MAP2表达的影响[J].中华中医药杂志，2021，36（9）：5473-5476.
[20] 郑香春，侯敏哲，武晓林，等.针药协同对难治性癫痫大鼠动物行为学及P-gp/MDR1的影响[J].中华中医药杂志，2018，33（11）：5140-5142.
[21] 钟向阳，李秋琼.婴儿痉挛症采用针药结合分型论治的临床研究[J].中国现代药物应用，2017，11（24）：126-128.
[22] 华显娇.穴位按摩对难治性癫痫大鼠学习记忆能力及海马细胞因子的影响[J].光明中医，2021，36（16）：2715- 2716.
[23] 刘玉堂，陈霄.穴位埋药线配合丙戊酸钠片治疗婴儿痉挛症36例[J].陕西中医学院学报，2011，34（4）：64-65.
[24] 单萍，张继龙，笱玉兰，等.柴胡皂苷a抑制PTZ诱导小鼠海马星形胶质细胞增殖和多药转运蛋白的表达[J].中国中医基础医学杂志，2020，26（10）：1461-1465.
[25] 徐沛，戴其军，柯进.柴胡皂苷a对颞叶癫痫神经的保护作用机制研究[J].中西医结合心脑血管病杂志，2022， 20（3）：450-454.
京公网安备 11010502046598号