Abstract：Objective To investigate the value of ultrasound-guided thyroid fine needle aspiration cytology (US-FNAB) and contrast-enhanced ultrasound (CEUS) in the qualitative diagnosis of thyroid imaging reporting and data system (TI-RADS) class 4 thyroid nodules. Methods The clinical data of 298 patients with TI-RADS class 4 thyroid nodules admitted to Ninth Hospital of Xi’an from January 2019 to December 2021 were retrospectively analyzed, a total of 326 thyroid nodules were confirmed by postoperative pathological examination, included 182 malignant nodules and 144 benign nodules. All patients underwent CEUS examination, US-FNAB examination, and combined US-FNAB and CEUS examination. Postoperative pathological examination as the gold standard, the benign and malignant detection of US-FNAB, CEUS, and their combined examination, the diagnostic value of US-FNAB, CEUS, and their combined examination were compared between the two groups, and the characteristics of CEUS perfusion and US-FNAB needle sensation of benign and malignant nodules were recorded. Results CEUS detected 180 cases of malignant TI-RADS class 4 thyroid nodules and 146 cases of benign TI-RADS class 4 thyroid nodules; US-FNAB detected 181 cases of malignant and 145 cases of benign; 208 cases of malignant and 118 cases of benign by jointly detected. The results of CEUS, US-FNA, and combined examination were consistent with those of postoperative pathological examination. The perfusion of CEUS in malignant showed low enhancement, while that in benign showed high enhancement or equal enhancement. In the malignant, the proportion of needle sensation in the US-FNAB was 81.77%, which was higher than 19.31% in the benign group (P＜0.05). Conclusion CEUS, US-FNA, and combined examination can effectively determine the benign and malignant of TI-RADS class 4 thyroid nodules, CEUS-enhanced features and US-FNAB acupuncture can provide the basis, and the combined examination of US-FNAB and CEUS have high sensitivity in the identification of benign and malignant, and have high diagnostic value.
乔旭东. 超声引导下甲状腺细针穿刺细胞学检查与超声造影联合检查对甲状腺结节定性诊断的价值[J]. 中国医药导报, 2022, 19(34): 149-153.
QIAO Xudong. Value of ultrasound-guided fine needle aspiration cytology combined with contrast-enhanced ultrasound in the qualitative diagnosis of thyroid nodules. 中国医药导报, 2022, 19(34): 149-153.
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