Abstract：Objective To explore the medication rules of Professor Wei Wei in treating diarrhea predominant irritable bowel syndrome (IBS-D) based on data mining. Methods The data of IBS-D patients treated by Professor Wei Wei in Wangjing Hospital of China Academy of Chinese Medical Sciences from January 2016 to January 2021 were collected. Excel 2019, SPSS 20.0 and SPSS Modeler 18.0 were used to analyze the frequency, nature, flavour and channel tropism of prescription drugs, strong related drugs and core components. Results Two hundred and thirty-seven prescriptions were collected, involving 91 kinds of traditional Chinese medicine, frequency of traditional Chinese medicine was 3 014 times in total. The most frequently used drugs were tonifying deficiency drug and digestant drug. The top five drug use frequencies were Pseudostellariae Radix, Myristicae Semen, Psoraleae Fructus, Setariae Fructus Germinatus, Hordei Fructus Germinatus. The drug nature was mainly warm; the drug flavours were mainly pungent, bitter and sweet; spleen and stomach channels were the main channel tropism. Combination of drugs with correlation frequency more than 100 times was 14 groups. Four groups of core medicine combinations were obtained according to the results of cluster analysis. Conclusion Professor Wei Wei mostly uses tonifying dificiency drug and digestant drug in the treatment of IBS-D. The main treatment principle is to strengthen the spleen and warm the kidney, regulating stomach and benefiting qi, help the spleen and stomach transport.
陈格格 潘雨烟 崔玉容 罗梦雪 国嵩 苏晓兰 魏玮. 基于数据挖掘探讨魏玮教授治疗腹泻型肠易激综合征的用药规律[J]. 中国医药导报, 2022, 19(34): 108-112.
CHEN Gege PAN Yuyan CUI Yurong LUO Mengxue GUO Song SU Xiaolan WEI Wei. Exploration on medication rules of Professor Wei Wei in the treatment of diarrhea predominant irritable bowel syndrome based on data mining. 中国医药导报, 2022, 19(34): 108-112.
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