Research progress of Notch signaling pathway in prostate cancer
LU Sheng CHEN Jie TIAN Lang ZHAO Wei CHEN Zhiwei WANG Yan
Department of Urinary Surgery, Zunyi Medical University Third Affiliated Hospital the First People’s Hospital of Zunyi, Guizhou Province, Zunyi 563000, China
Abstract：Prostate cancer is one of the common malignant tumors in the genitourinary system, which seriously threatens the health of patients. There are various treatment methods for prostate cancer, but the effect of various treatments is not ideal, and eventually it will develop into castration-resistant prostate cancer. Notch signaling pathway is currently one of the latest hotspots in cancer research. Notch signaling pathway is closely related to the occurrence, progression, and metastasis of various malignant tumors. This article reviews the role of Notch signaling pathway in prostate cancer (angiogenesis, cancer cell proliferation, and metastasis).
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