Efficacy of self-made Shengqing Yizhi Decoction in the treatment of mild vascular cognitive impairment after cerebral infarction with qi deficiency and phlegm obstruction syndrome
LI Fuhai1 WANG Xuehong1 LIU Ling2 ZHANG Xiaoguang1 CAO Haifang1 LI Xiangyang1 ZHAO Hanqing2
1.Department of Cerebral Diseases, Yixian Hospital of Traditional Chinese Medicine, Hebei Province, Yixian 074200, China;
2. College of Traditional Chinese Medicine, Hebei University, Hebei Province, Baoding 071000, China
Abstract：Objective To investigate the clinical efficacy of self-made Shengqing Yizhi Decoction in treating patients with mild vascular cognitive impairment after cerebral infarction with qi deficiency and phlegm obstruction syndrome. Methods A total of 172 patients with mild vascular cognitive impairment after cerebral infarction of qi deficiency and phlegm-blocked type in the Department of Cerebral Diseases, Yixian Hospital of Traditional Chinese Medicine of Hebei Province from January 2021 to October 2021 were selected as the research objects, and they were divided into control group and treatment group by random number table method, with 86 cases in each group. The control group was given Niergoline, Citicoline and Oxacetam Capsules for oral treatment. In the treatment group, self-made Shengqing Yizhi Decoction was added to based on the control group. The total treatment course of both groups was three months. The changes of traditional Chinese medicine syndromes and cognitive level were compared between the two groups before and after treatment. Results During the experiment, five patients in the control group fell off. After treatment, the total scores of traditional Chinese medicine syndrome in both groups were lower than those before treatment, and the treatment group was lower than the control group, the differences were statistically significant (P ＜ 0.05). After treatment, the mini-mental state examination scores and montreal cognitive assessment scores of the two groups were higher than those before treatment, and the treatment group was higher than the control group, the differences were statistically significant (P ＜ 0.05). Conclusion Shengqing Yizhi Decoction made at home mixed with western medicine is considerably more successful in treating vascular cognitive impairment than oral western medicine alone.
李福海1 王雪红1 刘灵2 张小光1 曹海芳1 李向阳1 赵汉青2 . 自拟升清益智汤治疗气虚痰阻型脑梗死后轻度血管性认知功能损害的效果[J]. 中国医药导报, 2022, 19(33): 116-119.
LI Fuhai1 WANG Xuehong1 LIU Ling2 ZHANG Xiaoguang1 CAO Haifang1 LI Xiangyang1 ZHAO Hanqing2. Efficacy of self-made Shengqing Yizhi Decoction in the treatment of mild vascular cognitive impairment after cerebral infarction with qi deficiency and phlegm obstruction syndrome. 中国医药导报, 2022, 19(33): 116-119.
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