Effect of repetitive transcranial magnetic stimulation in the treatment of cognitive dysfunction after ischemic stroke
LI Jing1 CUI Yu1 JIA Meiyan2▲
1.Department of Neurology, the Fifth People’s Hospital of Wuxi, Jiangsu Province, Wuxi 214000, China;
2.Department of Neurology, 904 Hospital of PLA Joint Logistics Support Force, Jiangsu Province, Wuxi 214000, China
Abstract：Objective To investigate the effect of repetitive transcranial magnetic stimulation (rTMS) in the treatment of cognitive dysfunction after ischemic stroke. Methods A total of 82 patients with cognitive dysfunction after ischemic stroke admitted to the Fifth People’s Hospital of Wuxi, Jiangsu Province from March 2018 to March 2021 were selected. According to the random number table method, they were divided into single group (Nimodipine, four consecutive weeks) and combined group (rTMS+ Nimodipine, four consecutive weeks), with 41 cases in each group. The Montreal cognitive assessment (MoCA) score, cerebral circulation dynamics index, modified Barthel index (MBI), and stroke specific quality of life (SS-QOL) scale score before and after four weeks of treatment were analyzed. Results Among the 82 patients, five dropped out and the remaining 77 cases were included, including 40 cases in the single group and 37 cases in the combined group. After four weeks of treatment, the scores of MoCA, MBI, SS-QOL, mean cerebral blood flow, and mean cerebral flow velocity in the two groups were higher than those before treatment, and the vascular resistance was lower than that before treatment; the scores of MoCA, MBI, SS-QOL, mean cerebral blood flow, and mean velocity in the combined group were higher than those in the single group, and the vascular resistance was lower than that in the single group (P ＜ 0.05). There was no significant difference in the total incidence of adverse reactions between the two groups (P ＞ 0.05). Conclusion rTMS is effective in the treatment of cognitive dysfunction after ischemic stroke, which can effectively improve the cognitive function of patients and promote the increase of cerebral blood flow, with good safety, and can be popularized in clinical practice.
李靖1 崔羽1 贾美岩2▲. 重复经颅磁刺激治疗缺血性脑卒中后认知功能障碍的效果[J]. 中国医药导报, 2022, 19(32): 80-83.
LI Jing1 CUI Yu1 JIA Meiyan2▲. Effect of repetitive transcranial magnetic stimulation in the treatment of cognitive dysfunction after ischemic stroke. 中国医药导报, 2022, 19(32): 80-83.
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