Diagnostic value of CT features in different pathological subtypes of lung adenocarcinoma
ZHANG Pengju1 LI Tianran1 LI Wenping2 XU Jinhuan2 ZHAO Shaohong2▲#br#
1.Department of Diagnostic Radiology, the Fourth Medical Center of General Hospital of the Chinese People’s Liberation Army, Beijing 100048, China; 2.Department of Diagnostic Radiology, the First Medical Center of General Hospital of the Chinese People’s Liberation Army, Beijing 100853, China
Abstract：Objective To investigate the diagnostic value of the CT features of pure ground-glass nodules (pGGN) in different pathological subtypes lung adenocarcinoma, and to provide imaging support for the management and treatment of pGGN. Methods The clinical data of 215 patients (236 nodules) with pGGN ≤2 cm in diameter and pathologically confirmed early lung adenocarcinoma at the First Medical Center of General Hospital of the Chinese People’s Liberation Army from January to December 2019 were analyzed. According to the pathological subtypes of pGGN, they were divided into preinvasive lesions-minimally invasive adenocarcinoma group (117 nodules), lepidic predominant adenocarcinoma group (77 nodules), and non-lepidic predominant adenocarcinoma group (42 nodules). The clinical features and CT features of the three groups were compared; receiver operating characteristic curves of diameter, CT value, and combined detection were drawn to predict the diagnostic efficacy of invasive predominant adenocarcinoma. Results There were significant differences in lobulation, spiculation, vascular changes, diameter, and CT value among three components (P ＜ 0.05). Diameter and CT value were positively correlated with pathological subtype (r ＝ 0.302, 0.352, P ＜ 0.05). Lobulation, vascular changes, diameter, and CT value were the influencing factors of invasive pulmonary adenocarcinoma (OR ＞ 1, P ＜ 0.05). The area under the curve of invasive predominant adenocarcinoma diagnosed by the combined detection of diameter and CT value was greater than that detected by each index alone. Conclusion The CT features of pGGN are related to its pathological subtype to some extent. Attention should be paid to morphological changes such as lobulation, spiculation, and vascular changes.
张鹏举1 李天然1 李文平2 许金环2 赵绍宏2▲. CT征象对不同病理亚型肺腺癌的诊断价值[J]. 中国医药导报, 2022, 19(31): 10-13,21.
ZHANG Pengju1 LI Tianran1 LI Wenping2 XU Jinhuan2 ZHAO Shaohong2▲. Diagnostic value of CT features in different pathological subtypes of lung adenocarcinoma. 中国医药导报, 2022, 19(31): 10-13,21.
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