Clinical application of classical prescriptions in the treatment of heart failure
GUO Yuna1 CHEN Liming2 LIU Kun1#br#
1.Department of Integrated Internal Medicine, Guang’anmen Hospital, Beijing 100053, China;
2.Basic Medicine Academy, Shanxi University of Chinese Medicine, Shaanxi Province, Xianyang 712046, China
Abstract：Heart failure is the terminal stage of the progression of various heart diseases, and its pathological mechanisms mainly include oxidative stress, inflammatory response, mitochondrial dysfunction, and abnormal calcium cycle. At present, western medicines for the treatment of heart failure mainly include angiotensin receptor enkephalinase inhibitor, angiotensin-converting enzyme inhibitor, angiotensin Ⅱ receptor blocker, β-receptor blocker blockers, aldosterone receptor antagonists, and sodium-glucose cotransporter 2 inhibitors. However, long-term use can lead to adverse reactions such as hypotension, electrolyte imbalance, and even increase the readmission rate. Reducing the fatality rate and readmission rate of heart failure and improving the quality of life of patients are clinical difficulties to be solved urgently. Traditional Chinese medicine has a long history of treating heart failure. Through long-term clinical observation, it has been found that traditional Chinese medicine has obvious advantages in improving the clinical symptoms of heart failure patients and reducing the recurrence rate. Based on the analysis of prescriptions related to heart failure in treatise on cold pathogenic diseases and synopsis of the golden chamber, this paper expounds the effects of Lingguizhugan Decoction, Zhenwu Decoction, Fuling Gancao Decoction, Xiaoqinglong Decoction, Guizhi Qushaoyao Decoction and Shenqi Pills in the development of heart failure. Different stages of application, explore the application of traditional Chinese medicine in the treatment of heart failure, in order to better guide the clinical.
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