Abstract：Objective To investigate the effect of optimized nutritional pathway on gastrointestinal function and immune indexes after colorectal cancer (CRC) surgery. Methods A total of 136 patients with CRC who underwent radical resection in the First People’s Hospital of Lianyungang, Jiangsu Province from April 2018 to May 2021 were selected. According to the random number table method, the patients were divided into routine group (n = 68, with routine nutritional care) and optimization group (n = 68, with optimized nutritional path), the recovery time of gastrointestinal function, immune indexes, postoperative nutritional risk score, and incidence of complications were compared between the two groups. Results The time of bowel sounds, time of first anal exhaust, time of first defecation, time of first eating, time of resuming normal eating, and incidence of complications in the optimization group were lower than those in the conventional group (P ＜ 0.05). The levels of CD4+, CD8+, and CD4+/CD8+ in the two groups at seven days postoperative were lower than those at one day before operation, and the levels of CD4+ and CD4+/CD8+ in the optimization group were higher than those in the conventional group, and the level of CD8+ was lower than that in the conventional group (P ＜ 0.05). The nutritional risk scores of the two groups at seven days after operation were lower than those at enrollent, and the optimization group was lower than the conventional group (P ＜ 0.05). Conclusion The optimized nutritional pathway in CRC is helpful to improve gastrointestinal function, immune indicators and nutritional level, and reduce the risk of postoperative complications.
熊兰彩 骆炯 徐小玮. 优化营养路径对结直肠癌术后胃肠功能及免疫指标的影响[J]. 中国医药导报, 2022, 19(29): 165-168.
XIONG Lancai LUO Jiong XU Xiaowei. Effect of optimized nutritional pathway on gastrointestinal function and immune indexes after colorectal cancer surgery. 中国医药导报, 2022, 19(29): 165-168.
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