Abstract：Objective To observe the effect of Yiqi Huoluo Shengji Decoction on diabetic foot patients with qi deficiency and blood stasis type. Methods A total of 124 diabetic foot patients admitted to the First People’s Hospital of Lianyungang of Jiangsu Province from February 2020 to August 2021 were selected as the research subjects. They were randomly divided into control group and study group according to the random number table method, with 62 cases in each group. The control group was given vacuum sealing drainage treatment on the basis of conventional treatment, and study group was given Yiqi Huoluo Shengji Decoction on the basis of control group. Both groups were treated for eight weeks. The traditional Chinese medicine symptom scores and clinical efficacy of two groups were compared, the changes of wound healing, peripheral nerve sensory threshold, and dorsum of foot blood flow between two groups were recorded; the occurrence of adverse events during treatment in two groups was recorded. Results After treatment, the traditional Chinese medicine syndrome scores of the main symptom and secondary symptom in both groups were lower than those before treatment, and those in study group was lower than those in control group, and the differences were statistically significant, (P < 0.05). The curative effect of study group was better than that of control group, and the difference was statistically significant (P < 0.05). The appearance time of foot ulcer granulation tissue and wound healing time in study group were shorter than those in control group (P < 0.05). After treatment, the peripheral nerve sensory threshold in two groups was lower than that before treatment, that of study group was lower than that of control group, and the differences were statistically significant (P < 0.05). After treatment, inner diameter of blood vessels, blood flow velocity, and pulsatility index in both groups were higher than those before treatment, and those in study group were higher than those in control group, and the differences were statistically significant (P < 0.05). There was no significant difference in the total incidence of adverse events between two groups (P > 0.05). Conclusion Yiqi Huoluo Shengji Decoction can enhance the therapeutic effect, accelerate wound healing, and improve peripheral nerve sensory function and blood circulation in patients with diabetic foot due to qi deficiency and blood stasis, with good safety.
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