中国多囊卵巢综合征患者焦虑抑郁患病率的meta分析

doi:10.20047/j.issn1673-7210.2022.27.21

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摘要目的了解中国多囊卵巢综合征（PCOS）患者焦虑抑郁情况。方法检索中国知网、万方数据知识服务平台、维普网、中国生物医学文献服务系统、PubMed、EMbase、The Cochrane Library、Web of Science核心合集数据库，检索时间为建库至2021年9月，收集关于中国PCOS患者焦虑抑郁患病情况的调查研究。采用Stata 12.0软件对焦虑抑郁患病率进行meta分析。结果共纳入9篇文献，meta分析显示，我国PCOS患者焦虑患病率为22%（95%CI：20%~24%），抑郁的患病率为30%（95%CI：28%~32%）。亚组分析显示，近5年内PCOS焦虑患病率为24%（95%CI：21%~27%），抑郁患病率为28%（95%CI：26%~31%）；近5~10年PCOS焦虑患病率为16%（95%CI：11%~21%），抑郁患病率为30%（95%CI：24%~36%）；10年以上PCOS焦虑患病率为23%（95%CI：19%~27%），抑郁患病率为37%（95%CI：32%~42%）。华南地区焦虑患病率为30%（95%CI：25%~36%），抑郁患病率为29%（95%CI：23%~34%）；华北地区焦虑患病率为27%（95%CI：22%~32%），抑郁患病率为38%（95%CI：33%~42%）；华东地区焦虑患病率为16%（95%CI：13%~20%），抑郁患病率为33%（95%CI：29%~38%）；西南地区焦虑患病率为22%（95%CI：19%~26%），抑郁患病率为24%（95%CI：21%~28%）。结论我国PCOS患者焦虑抑郁呈高发趋势，应加强对PCOS患者不良情绪的管理，预防和干预并行，探寻有效情绪管理手段。

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	严欣王连红郭云梅刘颖丁锐

关键词 ：多囊卵巢综合征, 焦虑, 抑郁, 患病率, meta分析

Abstract：Objective To understand the anxiety and depression of patients with polycystic ovary syndrome (PCOS) in China. Methods The databases includes CNKI, Wanfang Data Knowledge Service Platform, VIP, CBM, PubMed, EMbase, The Cochrane Library, and Web of Science core collection were searched by computer, the retrieval time was from the database construction to September 2021. The investigation and research on the anxiety and depression of PCOS patients in China were collected. The prevalence of anxiety and depression was analyzed using Stata 12.0 software. Results A total of nine literatures were included. Meta analysis showed that the prevalence of anxiety in PCOS patients in China was 22% (95%CI: 20%-24%), and the prevalence of depression was 30% (95%CI: 28%-32%). Subgroup analysis showed that the prevalence of PCOS anxiety was 24% (95%CI: 21%-27%) and the prevalence of depression depression was 28% (95%CI: 26%-31%) in recent five years; the prevalence of PCOS anxiety and depression was 16% (95%CI: 11%-21%) and the prevalence of depression was 30% (95%CI: 24%-36%) in recent five to ten years; the prevalence of PCOS anxiety was 23% (95%CI: 19%-27%), and the prevalence of depression was 37% (95%CI: 32%-42%) over ten years. The prevalence of anxiety was 30% (95%CI: 25%-36%) and the prevalence of depression was 29% (95%CI: 23%-34%) in South China; the prevalence of anxiety was 27% (95%CI: 22%-32%) and the prevalence of depression was 38% (95%CI: 33%-42%) in North China; the prevalence of anxiety was 16% (95%CI: 13%-20%) and the prevalence of depression was 33% (95%CI: 29%-38%) in East China; the prevalence of anxiety was 22% (95%CI: 19%-26%) and the prevalence of depression was 24% (95%CI: 21%-28%) in Southwest China. Conclusion Anxiety and depression in PCOS patients in China are in a high incidence trend. Therefore, it is necessary to strengthen the management of PCOS patients’ adverse emotions to explore effective emotional management means by both prevention and intervention.

Key words： Polycystic ovary syndrome Anxiety Depression Prevalence Meta analysis

基金资助:贵州省卫生健康委科学技术基金项目（gzwjkj2019-1-018）；
遵义医科大学学术新苗培养及创新探索专项项目（黔科合平台人才[2017]5733-077）。

作者简介: 严欣（1998-），女，遵义医科大学护理学院2020级护理专业在读硕士研究生；研究方向：妇女健康与延续性护理。

引用本文:

严欣王连红郭云梅刘颖丁锐. 中国多囊卵巢综合征患者焦虑抑郁患病率的meta分析[J]. 中国医药导报, 2022, 19(27): 92-96.
YAN Xin WANG Lianhong GUO Yunmei LIU Ying DING Rui . Meta analysis on prevalence of anxiety and depression of patients with polycystic ovary syndromen in China. 中国医药导报, 2022, 19(27): 92-96.

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