Abstract:Objective To study the effect of the synergistic effect of PM2.5 and air temperature on the death population of residents with respiratory diseases. Methods A generalized additive model based on time series was used to explore the health effects of PM2.5 concentration and air temperature on the population in this area, and a bivariate response surface was established to evaluate the interaction between PM2.5 and air temperature on the death of residents from respiratory diseases. Results From 2014 to 2018, there were 25 971 deaths of residents in the area due to respiratory diseases, with an average daily death toll of 14 cases. The effect of PM2.5 on the death of residents’ respiratory diseases had a lag effect, and the effect was the largest when the lag was 2 d, with every increase of 10 μg/m3. Residents’ daily risk of death from respiratory diseases was increased by 0.36% (95%CI: 0, 0.72%). Under the conditions of low temperature and high concentration of PM2.5, the mortality risk of respiratory diseases was the highest, and low temperature and PM2.5 had a synergistic effect on the mortality risk of respiratory diseases. Conclusion Atmospheric PM2.5 exposure can increase the risk of death from respiratory diseases in residents, and low air temperature has a synergistic effect.
张维宁 孙媛媛 申喜凤 李美婷 南嘉乐 高东平. 气温与PM2.5对呼吸系统疾病死亡的协同效应研究[J]. 中国医药导报, 2022, 19(27): 7-11.
ZHANG Weining SUN Yuanyuan SHEN Xifeng LI Meiting NAN Jiale GAO Dongping. Study of the synergistic effect of air temperature and PM2.5 on the death of respiratory diseases. 中国医药导报, 2022, 19(27): 7-11.
[1] Landrigan PJ,Fuller R,Acosta NJR,et al. The Lancet Commission on pollution and health [J]. Lancet,2018,391(10119):462-512.
[2] Schraufnagel DE,Balmes JR,Cowl CT,et al. Air Pollution and Noncommunicable Diseases:A Review by the Forum of International Respiratory Societies’ Environmental Committee,Part 1:The Damaging Effects of Air Pollution [J]. Chest,2019,155(2):409-416.
[3] Li R,Zhou R,Zhang J. Function of PM2.5 in the pathogenesis of lung cancer and chronic airway inflammatory diseases [J]. Oncol Lett,2018,15(5):7506-7514.
[4] Renzi M,Scortichini M,Forastiere F,et al. A nationwide study of air pollution from particulate matter and daily hospitalizations for respiratory diseases in Italy [J]. Sci Total Environ,2022,807(Pt 3):151034.
[5] 张镇权,王绍华,吴志乐,等.北京市延庆区大气污染物对呼吸系统疾病门急诊量的影响[J].中华疾病控制杂志,2019,23(7):822-827,834.
[6] 陈帅,周海泓,于蕾,等.空气污染物对呼吸系统疾病门诊量影响的时间序列分析[J].江苏预防医学,2022,33(1):8-11.
[7] WHO. Climate change and health [EB/OL].(2021-10-30) [2021-10-30]. https://www.who.int/news-room/fact-sheets/detail/climate-change-and-health.
[8] Wang C,Chen R,Kuang X,et al. Temperature and daily mortality in Suzhou,China:a time series analysis [J]. Sci Total Environ,2014(466/467):985-990.
[9] 罗焕金,曾四清,胡梦珏,等.极端低温对呼吸系统疾病住院人数影响的时间序列分析[J].华南预防医学,2014, 40(6):504-511.
[10] 中国疾控中心环境与健康相关产品安全所.共享杯版-我国某地区2014—2018年死因及环境监测数据[EB/OL].国家人口健康科学数据中心数据仓储PHDA,2021.https://doi.org/10.12213/11.A0006.202109.581.V1.0.
[11] 赵海莉,原悦,李晓芹,等.兰州市西固区大气污染对呼吸系统疾病的健康效应研究[J].生态学报,2022(11):1-14.
[12] 樊琳,顾清,曾强.广义相加模型在大气污染流行病学研究中的应用进展[J].环境与职业医学,2019,36(7):676-681.
[13] 王永星,闫晓娜,张杰,等.郑州市日均气温对居民非意外死亡影响的分布滞后非线性模型分析[J].郑州大学学报(医学版),2021,56(5):652-657.
[14] Gasparrini A. Distributed Lag Linear and Non-Linear Models in R:The Package dlnm [J]. J Stat Softw,2011:43(8):1-20.
[15] 杨敏娟,赵宜静,王文朋,等.上海市浦东新区大气PM2.5与气温交互作用对居民死亡的影响[J].上海预防医学,2020,32(4):283-289.
[16] Chen K,Wolf K,Breitner S,et al. Two-way effect modifications of air pollution and air temperature on total natural and cardiovascular mortality in eight European urban areas [J]. Environ Int,2018,116:186-196.
[17] 刘芳盈,刘晓利,李平,等.淄博市主城区大气PM2.5与呼吸系统疾病门诊人次的相关性研究[J].环境与健康杂志,2019,36(3):223-226.
[18] 宋和佳,程义斌,李永红,等.气温和大气颗粒物对哈尔滨市人群死亡影响的交互作用[J].环境卫生学杂志,2021, 11(4):318-325.
[19] 欧奕含,张小玲,张莹,等.西安BC、PM2.5与气温协同对心脑血管疾病死亡的影响[J].中国环境科学,2021,41(9):4415-4425.
[20] Xu Q,Wang S,Guo Y,et al. Acute exposure to fine particulate matter and cardiovascular hospital emergency room visits in Beijing,China [J]. Environ Pollut,2017, 220(Pt A):317-327.
[21] 中华人民共和国生态环境部.GB 3095-2012 国家环境空气质量标准[S].北京:中国环境科学出版社,2012.
[22] 王子豪,沈卓之,吴芸芸,等.重庆市主城区域2014—2018年大气污染物PM2.5对居民呼吸系统疾病死亡影响的时间序列研究[J].重庆医学,2020,49(22):3688-3692.
[23] 曾婕,刘睿聪,陈剑宇,等.成都市PM2.5水平与人群呼吸系统疾病死亡的时间序列研究[J].江苏预防医学,2017, 28(2):144-146,168.
[24] 冯建纯,孙红梅,杜月菊,等.石家庄市PM2.5浓度对居民死亡的急性影响分析[J].现代预防医学,2018,45(4):603-608.
[25] 洪也,张莹,马雁军,等.沈阳大气污染物与气象因素对呼吸疾病门诊数的影响[J].中国环境科学,2020,40(9):4077-4090.
[26] 张莹,辛金元,马盼,等.成都市气温与PM2.5和O3交互作用对疾病死亡人数的影响研究[J].中国环境科学,2021,41(8):3887-3895.