Medication experience in the treatment of arthralgia syndrome based on data mining of Ren Zhai Zhi Zhi Fang Theory
YANG Yue1 LI Lu2 YUAN Bo2 CUI Weilu3 GE Lin2 CAO Wei1
1.Wang Jing Hospital of China Academy of Chinese Medical Sciences, Beijing 100102, China;
2.Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China;
3.Beijing University of Chinese Medicine, Beijing 100029, China
Abstract：Objective To study Yang Shiying’s medication experience in treating arthralgia syndrome in Ren Zhai Zhi Zhi Fang Theory. Methods The internal prescription for the treatment of arthralgia syndrome in Ren Zhai Zhi Zhi Fang Theory was sorted out and entered into the traditional Chinese medicine inheritance computing platform V3.0 for statistics and analysis of medication rules, and the nature and flavour, channel tropism, efficacy, frequency, association rules and clustering of drugs were discussed. Results A total of 47 decoction for internal administration were recorded, with a total of 100 traditional Chinese medicines, most of which were warm, calm nature, sweet, pungent, and bitter flavour drugs. The drugs mainly returned to the spleen, heart, liver, and lung channels, and the effects were mostly to replenish deficiency, relieve superficies, warming interior, promote blood circulation, and remove blood stasis and so on. Twenty-three traditional Chinese medicines with drug frequency ≥six, 28 high-frequency drug combinations, 24 association rules between drugs were obtained, and four kinds of prescriptions were obtained by clustering. Conclusion Yang Shiying believes that the etiology and pathogenesis of arthralgia syndrome were mainly external evil invasion and internal positive deficiency; kidney cold and blood stasis; spleen injury and phlegm stagnation. The treatment of arthralgia syndrome is not only dispelling wind and eliminating dampness, but also paying attention to “kidney”, “spleen”, “phlegm” and “blood”, using the methods of warming kidney and nourishing blood, strengthening spleen and eliminating phlegm, warming meridian, and activating blood, taking into account both internal and external evil, which can provide certain reference and basis for clinical treatment of arthralgia syndrome.
杨越1 李露2 袁博2 崔玮璐3 葛琳2 曹炜1. 基于数据挖掘《仁斋直指方论》治疗痹证的用药经验[J]. 中国医药导报, 2022, 19(26): 19-23.
YANG Yue1 LI Lu2 YUAN Bo2 CUI Weilu3 GE Lin2 CAO Wei1. Medication experience in the treatment of arthralgia syndrome based on data mining of Ren Zhai Zhi Zhi Fang Theory. 中国医药导报, 2022, 19(26): 19-23.
京公网安备 11010502046598号