高流量湿化氧疗对颅脑损伤气管切开非机械通气患者的影响

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摘要目的探讨高流量湿化氧疗（HHFNC）对颅脑损伤气管切开非机械通气患者的影响。方法选取2016年3月~2018年3月重庆市黔江中心医院收治的60例颅脑损伤气管切开非机械通气患者，依据治疗措施不同进行分组，对照组和观察组，每组各30例，对照组和观察组分别行常规的湿化氧疗和HHFNC。观察两组患者气道开放后3、7、10、14 d医院获得性肺炎的发生率，观察两组患者平均吸痰次数、痰痂形成率、痰液黏稠度及脱机后气道湿化效果。结果观察组患者医院获得性肺炎的发生率、吸痰次数、痰痂形成率及痰液黏稠度均低于对照组，脱机后气道湿化效果优于对照组，差异均有统计学意义（P < 0.05）。结论 HHFNC治疗颅脑损伤气管切开非机械通气患者，可降低医院获得性肺炎的发生率、吸痰次数、痰痂形成率，改善痰液黏稠度，提高气道湿化效果，值得临床推广应用。

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	谭勇徐立勇▲

关键词 ：高流量湿化氧疗, 颅脑损伤, 气管切开, 非机械通气

Abstract：Objective To investigate the effect of humidified high flow nasal cannula (HHFNC) on patients with tracheal incision and non-mechanical ventilation. Methods Sixty patients with cranial incision and non-mechanical ventilation who were admitted to Minjiang Central Hospital of Chongqing from March 2016 to March 2018 were selected. Grouped according to treatment measures, control group and the observation group, with 30 cases in each group. Conventional humidified oxygen therapy and HHFNC were performed in the control group and the observation group, respectively. The incidence of hospital acquired pneumonia was observed at 3, 7, 10, 14 d after airway opening in both groups. The average number of sputum aspiration, the formation rate of sputum callus, the viscosity of sputum, and the airway wetting result after offline were observed. Results The incidence of hospital-acquired pneumonia, number of sucking, rate of sputum formation and the viscosity of sputum in the observation group were lower than those in the control group, the airway wetting result of the patients in the group was better than that of the control group, and the differences were statistically significant (P < 0.05). Conclusion HHFNC for patients with craniocerebral injury with tracheotomy and non-mechanical ventilation can reduce the incidence of hospital-acquired pneumonia, the average number of sputum aspiration, and the formation rate of sputum callus, improve the viscosity of sputum, and improve the airway wetting result. It is worthy of clinical application.

Key words： Humidified high flow nasal cannula Craniocerebral injury Tracheotomy Non-mechanical ventilation

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引用本文:

谭勇徐立勇▲. 高流量湿化氧疗对颅脑损伤气管切开非机械通气患者的影响[J]. 中国医药导报, 2018, 15(28): 92-95.
TAN Yong XU Liyong▲. The influence of tracheotomy non-mechanical ventilation for craniocerebral injury patients by high flow oxygen therapy humidification. 中国医药导报, 2018, 15(28): 92-95.

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