Abstract:Objective To understand the prevalence and risk factors of allergic rhinitis among primary and secondary school students in Hohhot. Methods A cross-sectional survey method was used to conduct a questionnaire survey among primary and secondary school students aged 7 to 18 in six schools in Hohhot. The research subjects were divided into allergic rhinitis (AR) group and non AR group. The related data of the two groups were compared, and logistic regression analysis was used for multivariate analysis. Results A total of 5 747 primary and secondary school students were investigated, and the reported rate of AR among primary and secondary school students in Hohhot was 18.51%. Univariate analysis showed that there were significant differences in gender, age, ethnicity, body mass index, place of residence, parents with allergic rhinitis, mode of delivery, breastfeeding, neonatal jaundice, mother drinking alcohol during pregnancy, living in a city, having pets at home, having flowers or plants at home, someone smoking at home, and plush toys at home between AR group and non AR (P < 0.05). Multivariate logistic regression analysis showed that females, household flowers and plants were protective factors for allergic rhinitis in primary and secondary school students (OR < 1, P < 0.05); Mongolian nationality, obesity, living in the city, parents suffering from AR, cesarean section, neonatal jaundice, keeping pets at home, and someone smoking at home were risk factors for AR in primary and middle school students (OR > 1, P < 0.05). Conclusion The reported rate of AR among primary and secondary school students in Hohhot is at a high level. Students and parents should pay attention, find the reasons and take corresponding countermeasures.
刘畅 迟宝峰. 呼和浩特地区中小学生变应性鼻炎流行状况及危险因素分析[J]. 中国医药导报, 2022, 19(23): 32-35.
LIU Chang CHI Baofeng. Analysis of epidemiological status and risk factors of allergic rhinitis among primary and secondary school students in Hohhot area. 中国医药导报, 2022, 19(23): 32-35.
[1] 中华耳鼻咽喉头颈外科杂志编辑委员会鼻科组,中华医学会耳鼻咽喉头颈外科学分会鼻科学组.中国变应性鼻炎诊断和治疗指南(2022年,修订版)[J].中华耳鼻咽喉头颈外科杂志,2022,57(2):106-129.
[2] Bro■ek JL,Bousquet J,Agache I,et al. Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines-2016 revision [J]. J Allergy Clin Immunol,2017,140(4):950-958.
[3] Hu SJ,Wei P,Kou W,et al. Prevalence and risk factors of allergic rhinitis:a Meta-analysis [J]. J Clin Otorhinolaryngol Head Neck Surg,2017,31(19):28-34.
[4] 马婷婷,庄严,石海云,等.内蒙古自治区草原地区儿童变应性鼻炎流行病学调查[J].中华耳鼻咽喉头颈外科杂志,2019,54(8):571-575.
[5] Huang SK,Zhang Q,Qiu Z,et al. Mechanistic impact of outdoor air pollution on asthma and allergic diseases [J]. J Thorac Dis,2015,7(1):23-33.
[6] Asher MI,Weiland SK. The International Study of Asthma and Allergies in Childhood(ISAAC). ISAAC Steering Committee [J]. Clin Exp Allergy,1998,28(5):52-66.
[7] Burney PG,Luczynska C,Chinn S,et al. The European Community Respiratory Health Survey [J]. Eur Respir J,1994,7(5):954-960.
[8] 中华人民共和国国家卫生健康委员会.GB/T 586-2018 中国标准书号[S].北京:中国标准出版社,2018.
[9] Liu W,Zeng Q,Zhou L,et al. Association of leptin with disease severity and inflflammation indicators in Chinese obese children with allergic rhinitis [J]. Pediatr Allergy Immunol,2018,29(2):186-193.
[10] Han YY,Forno E,Gogna M,et al. Obesity and rhinitis in a nationwide study of children and adults in the United States [J]. J Allergy Clin Immunol,2016,137(5):1460-1465.
[11] Luo X,Xiang J,Dong X,et al. Association between obesity and atopic disorders in Chinese adults:an individually matched case-control study [J]. BMC Public Health,2013,13(1):12-16.
[12] Wei CC,Lin CL,Shen TC,et al. Neonatal jaundice and risks of childhood allergic diseases:a population-based cohort study [J]. Pediatr Res,2015,78(2):223-230.
[13] Lauer BJ,Spector ND. Hyperbilirubinemia in the newborn [J]. Pediatr Rev,2011,32(8):341-349.
[14] Das RR,Naik SS. Neonatal hyperbilirubinemia and childhood allergic diseases:a systematic review [J]. Pediatr Allergy Immunol,2015,26(1):2-11.
[15] Yu B,Dai L,Chen J,et al. Prenatal and neonatal factors involved in the development of childhood allergic diseases in Guangzhou primary and middle school students [J]. BMC Pediatr,2019,19(1):479.
[16] Mitselou N,Hallberg J,Stephansson O,et al. Adverse pregnancy outcomes and risk of later allergic rhinitis-Nationwide Swedish cohort study [J]. Pediatr Allergy Immunol,2020,31(5):471-479.
[17] Yang Z,Zheng W,Yung E,et al. Frequency of food group consumption and risk of allergic disease and sensitization in schoolchildren in urban and rural China [J]. Clin Exp Allergy,2015,45(12):1823-1832.
[18] Tong H,Gao L,Deng Y,et al. Prevalence of Allergic Rhinitis and Associated Risk Factors in 6 to 12 Years Schoolchildren From Wuhan in Central China:A Cross-sectional Study [J]. Am J Rhinol Allergy,2020,34(5):632-641.
[19] Singh S,Sharma BB,Salvi S,et al. Allergic rhinitis,rhin-oconjunctivitis,and eczema: prevalence and associated factors in children [J]. Clin Respir J,2018,12(2):547-556.
[20] 曾祥英,秦晨光,聂国明.武汉市4~14岁儿童过敏性鼻炎的危险因素分析[J].中国儿童保健杂志,2018,26(5):551-554.
[21] Feleszko W,Ruszczyński M,Jaworska J,et al. Environmental tobacco smoke exposure and risk of allergic sensitisation in children:a systematic review and meta-analysis [J]. Arch Dis Child,2014,9(11):985-992.
[22] 邵凤勤,陈春英,张庆华,等.儿童过敏性鼻炎过敏原调查和相关危险因素分析[J].中国妇幼保健,2021,36(18):4299-4302.
[23] 高玲,李果,许昱,等.湖北省枣阳市6~12岁儿童变应性鼻炎流行病学调查分析[J].临床耳鼻咽喉头颈外科杂志,2018,32(21):1641-1645,1650.
[24] Shargorodsky J,Garcia-Esquinas E,Umanskiy R,et al. Household pet exposure,allergic sensitization,and rhinitis in the U.S. population [J]. Int Forum Allergy Rhinol,2017,7(7):645-651.