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TVS-CEUS在宫颈癌术前临床分期诊断中的可行性研究
王英娈1      刘颖1▲      王来栋2      崔艳玲2      杨春晓3      张海鹏4
1.山东省淄博市市立医院超声科,山东淄博   255400;
2.山东省淄博市市立医院妇科,山东淄博   255400;
3.山东省淄博市市立医院普外科五病区(两腺),山东淄博   255400;
4.山东省淄博市市立医院病理科,山东淄博   255400
Feasibility study of TVS-CEUS in preoperative clinical staging diagnosis of cervical cancer
WANG Yingluan1   LIU Ying1▲   WANG Laidong2   CUI Yanling2   YANG Chunxiao3   ZHANG Haipeng4
1.Department of Ultrasound, Zibo Municipal Hospital, Shandong Province, Zibo   255400, China; 
2.Department of Gynecology, Zibo Municipal Hospital, Shandong Province, Zibo   255400, China; 
3.Ward Five, Department of General Surgery (Two Glands), Zibo Municipal Hospital, Shandong Province, Zibo   255400, China; 
4.Department of Pathology, Zibo Municipal Hospital, Shandong Province, Zibo   255400, China
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摘要 目的 评估经阴道超声造影(TVS-CEUS)技术在宫颈癌术前诊断及临床分期中的应用价值,并探讨行临床分期的可行性。 方法 选取2011年9月至2020年12月于山东省淄博市市立医院就诊且经手术病理证实的81例宫颈癌患者。所有患者术前均行经阴道彩色多普勒超声(TVCDS)及TVS-CEUS检查,评估病灶的性质并进行术前分期;观察良恶性淋巴结之间的图像差异。 结果 TVS-CEUS宫颈癌检出率高于TVCDS,差异有统计学意义(P < 0.05)。TVCDS诊断符合率为73.08%(57/78),Kappa值为0.536;TVS-CEUS诊断符合率为89.74%(70/78),Kappa值为0.824。盆腔转移淋巴结的声像表现为造影剂显像迟于周围正常软组织,呈弥漫性均匀低增强,且与周围组织无明显界限。 结论 TVS-CEUS提高了对宫颈癌的诊断能力及分期的准确性,对盆腔肿大淋巴结的性质判定也有一定价值。
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王英娈1 刘颖1▲ 王来栋2 崔艳玲2 杨春晓3 张海鹏4
关键词 宫颈癌经阴道超声超声造影分期诊断    
Abstract:Objective To evaluate the value of transvaginal contrast-enhanced ultrasound (TVS-CEUS) in preoperative diagnosis and clinical staging of cervical cancer, and to explore the feasibility of clinical staging. Methods A total of 81 patients with cervical cancer confirmed by surgery and pathology were selected from September 2011 to December 2020 in Zibo Municipal Hospital of Shandong Province. All patients underwent transvaginal color Doppler ultrasound (TVCDS) and TVS-CEUS examination before surgery to evaluate the nature of lesions and perform preoperative staging; the differences between benign and malignant lymph nodes were observed. Results The detection rate of cervical cancer of TVS-CEUS was higher than that of TVCDS, and the difference was statistically significant (P < 0.05). The diagnostic coincidence rate of TVCDS was 73.08% (57/78), and Kappa value was 0.536; the diagnostic coincidence rate of TVS-CEUS was 89.74% (70/78), and Kappa value was 0.824. The sonographic appearance of pelvic metastatic lymph nodes was later than the surrounding normal soft tissue with diffuse uniform low enhancement and no clear boundary with the surrounding tissue. Conclusion TVS-CEUS can improve the diagnostic ability and staging accuracy of cervical cancer, and has certain value in the determination of the nature of pelvic enlarged lymph nodes.
Key wordsCervical cancer    Transvaginal ultrasound    Ultrasound contrast    Staging diagnosis
    
基金资助:北京医学奖励基金会课题研究项目(YXJL2019 06880046);
山东省淄博市科学技术发展计划政策引导类项目(2014kj060020)。
通讯作者: ▲通讯作者   
作者简介: 王英娈(1983.5-),女,硕士;研究方向:妇产科及肌肉骨关节超声诊断。
引用本文:   
王英娈1 刘颖1▲ 王来栋2 崔艳玲2 杨春晓3 张海鹏4. TVS-CEUS在宫颈癌术前临床分期诊断中的可行性研究[J]. 中国医药导报, 2022, 19(22): 149-152.
WANG Yingluan1 LIU Ying1▲ WANG Laidong2 CUI Yanling2 YANG Chunxiao3 ZHANG Haipeng4. Feasibility study of TVS-CEUS in preoperative clinical staging diagnosis of cervical cancer. 中国医药导报, 2022, 19(22): 149-152.
链接本文:  
https://www.yiyaodaobao.com.cn/CN/     或     https://www.yiyaodaobao.com.cn/CN/Y2022/V19/I22/149

 

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