Abstract:Adenomyosis is a kind of gynecological disease that is difficult to treat. Its focus is progressive aggravation, which makes the uterus gradually increased. It is often accompanied by severe dysmenorrhea and excessive menstruation, so it is very difficult to treat. Wu Yuning, a famous medical teacher of capital state, has rich experience in the diagnosis and treatment of this disease. She believes that “phlegm, blood stasis, toxin and heat intermingle” is its basic pathogenesis, and the disease is located in the collaterals and uterus. Because the clinical symptoms of non menstrual period are not obvious, but the symptoms in menstrual period are serious, so she proposed to discuss the treatment in stages. For the treatment of non menstrual period, it is mainly to eliminate blood stasis and phlegm, remove toxicity for eliminating accumulation, and take into account the menstrual cycle. She is good at using insect medicine, and pays attention to strengthening righteousness, dispelling evil, and protecting stomach qi. Menstrual symptoms should be treated with “Tiaojing Decoction” to promote blood circulation and remove blood stasis, which is also used to relieve pain and regulate menstruation. She used the prescriptions flexibly to relieve the symptoms of dysmenorrhea and control the amount of menstruation. The drug is unique and the clinical effect is remarkable. In this paper, Wu Yuning’s clinical experience in the treatment of adenomyosis is summarized. Moreover, the academic experience of famous Chinese doctors can be learned, the level of treatment can also be improved. Last but not least, a typical medical case is attached for peer’s reference.