1.Department of Encephalopathy, Foshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Chinese Medicine, Guangdong Province, Foshan 528000, China;
2.Department of Encephalopathy, Shaanxi Province Hospital of Traditional Chinese Medicine, Shaanxi Province, Xi’an 710000, China
Abstract：Objective To explore Professor Tan Feng’s clinical experience of using “three early” therapy in the treatment of ischemic stroke based on data mining technology. Methods Chinese medicine prescriptions of ischemic stroke patients treated in the outpatients and inpatients of Professor Tan Feng in Foshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Chinese Medicine from January 2018 to June 2021 were collected. The traditional Chinese Medicine Inheritance Assistance Platform (V2.5) software was used for data analysis and mining by frequency analysis, association rules, complex entropy clustering analysis, and other methods. Results A total of 236 Chinese medicine prescriptions were screened, involving 127 Chinese medicine ingredients. The top five drug use frequency were Atractylodis Macrocephalae Rhizoma, Chuanxiong Rhizoma, Astragali Radix, Pinelliae Rhizoma, and Angelicae Sinensis Radix. The most frequently used drugs were harmonizing qi and blood drugs. The drug properties were mainly warm and flat, the drug tastes were mainly sweet and pungent, and the channel tropisms were mainly liver, spleen, and heart channels. Eighteen pairs of common Chinese medicine combinations were obtained by association rule analysis, and five potential new prescriptions were mined based on entropy clustering. Conclusion Professor Tan Feng believes that blood stasis runs through the course of ischemic stroke, and puts forward the “three early” therapy of traditional Chinese medicine in the treatment of ischemic stroke. The clinical application of drugs promoting blood circulation for removing blood stasis is emphasized, supplemented by drugs supplementing qi and dissipating phlegm, resolving stagnation for tranquilization, and the use of insect drugs for patients with chronic illness, and it can provide reference for clinical practice.
梁艳桂1 谭峰1 陈杰2 吴海科1 程南方1 陈文霖1. 基于数据挖掘探讨谭峰教授“三早”疗法治疗缺血性脑卒中的临证经验[J]. 中国医药导报, 2022, 19(19): 120-124.
LIANG Yangui1 TAN Feng1 CHEN Jie2 WU Haike1 CHENG Nanfang1 CHEN Wenlin1. Discussion the clinical experience of Professor Tan Feng’s “three early” therapy in the treatment of ischemic stroke based on data mining. 中国医药导报, 2022, 19(19): 120-124.
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